US4192869A
Expired / Lapsed
US
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Controlled improvement of the O2 release by intact erythrocytes with lipid vesicles
Assignee: Studiengesellschaft Kohle gGmbH
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Filing: 1978-10-17
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Granted: 1980-03-11
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Expires: 1998-10-17
Abstract
Abstract The invention provides erythrocytes of improved O 2 -release properties having fused thereto small allosteric effectors, f.i. inositol hexaphosphate-containing lipid vesicles. Also included in the invention is a method for making said erythrocytes and plasma containing said erythrocytes. The above-identified lipid vesicles provide an additional aspect of the invention.
Inventors
- 👤 Yves-Claude Nicolau
- 👤 Klaus Gersonde
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 14:45
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/12; A61K35/14; A61K35/18; A61K9/00; A61K9/10; A61K9/127; A61K9/48; A61K9/50; A61K9/5005; A61K9/5063; A61K9/5068
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
24 words
Lipid vesicles containing inositol hexaphosphate in which the lipid consists essentially of phosphatidylcholine:phosphatidylserine:cholesterol in the mole ratio 10 to 5:4 to 1:10 to 3.
Claim 2
Dependent Claim
24 words
Lipid vesicles containing inositol hexaphosphate in which the lipid consists essentially of phosphatidylcholine:phosphatidylserine:cholesterol in the mole ratio 10 to 5:4 to 1:10 to 3.
Claim 3
Dependent Claim
17 words
Lipid vesicles of claim 1 in which the phosphatidylcholine:phosphatidylserine and cholesterol are in the mole ratio 8:2:7.
Claim 4
Dependent Claim
18 words
Lipid vesicles of claim 1 in which the phosphatidylcholine:phosphatidylserine :phosphatidylserine and cholesterol are in the mole ratio 9:1:8.
Claim 5
Dependent Claim
17 words
Lipid vesicles of claim 1 in which the phosphatidylcholine:phosphatidylserine and cholesterol are in the mole ratio 8:4:7.
References Cited (Backward Citations)
US4016290A
Cited
US3957971A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-03-11 | 1983-09-10 | 1984-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-03-11 | 1987-09-10 | 1988-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-03-11 | 1991-09-10 | 1992-03-11 | $7700.00 | Window Closed / Lapsed |