US4192845A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sterilization process and apparatus for infusion solutions and the like filled in containers
Assignee: Vereinigte Edelstahlwerke AG
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Filing: 1978-03-27
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Granted: 1980-03-11
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Expires: 1998-03-27
Abstract
Abstract A sterilization apparatus includes a housing adapted for receiving a removable rack with open shelves supporting containers with the substance to be sterilized, a fan arranged at the top of the housing, and a cooling device for subsequent cooling of the sterilizing fluid introduced into the housing. To increase the uniformity of whirling of the fluid around the containers on different levels of the rack and thus to increase the heat transfer to, and the subsequent heat removal from the containers, a timing-and flow-controlling device is provided for cyclically changing the flow of the sterilizing fluid through the rack during the heating-up and cooling-down of the sterilization cycle, either by alternating the direction of the flow, or by distributing periodically partial streams through different shelves of the rack.
Inventors
- 👤 Karl Kalasek
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:45
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/24
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
75 words
In a process of sterilizing articles stacked on different levels in a closed chamber for a sterilization cycle, said sterilization cycle including heating-up and cooling-down periods, wherein the improvement comprises the steps of: introducing a stream of a heated sterilization fluid into said chamber; moving said fluid around said articles; and periodically changing the direction of said stream for time periods that are short relative to the heating-up and cooling-down periods of the sterilization cycle.
Claim 2
Dependent Claim
75 words
In a process of sterilizing articles stacked on different levels in a closed chamber for a sterilization cycle, said sterilization cycle including heating-up and cooling-down periods, wherein the improvement comprises the steps of: introducing a stream of a heated sterilization fluid into said chamber; moving said fluid around said articles; and periodically changing the direction of said stream for time periods that are short relative to the heating-up and cooling-down periods of the sterilization cycle.
Claim 3
Dependent Claim
42 words
In a process as claimed in claim 1, wherein the improvement further comprises the steps of dividing the stream of said fluid into at least two partial streams, and periodically directing said partial streams to the different levels of the stacked articles.
Claim 4
Dependent Claim
57 words
In a process according to claim 2 wherein the improvement further comprises the steps of: sensing the temperature on said different levels, comparing the sensed values to a predetermined average temperature, and directing said partial streams to said levels in response to corresponding differences between said sensed values and said predetermined average value to minimize said differences.
Claim 5
Dependent Claim
113 words
A sterilization apparatus comprising in combination: an openable and closeable housing for articles to be sterilized therein; support means to support said articles in said housing; means operable for introducing a heated sterilization fluid into said housing to sterilize said articles during a predetermined sterilization period; propulsion means operable for moving said fluid in a continuous flow near said articles in said housing; a cooling device at least partially disposed in said housing for cooling the articles during a cooling period following said sterilization period; and timing and controlling means for changing the direction of continuous flow of said fluid at time intervals that are short relative to the sterilization and cooling periods.
Claim 6
Dependent Claim
113 words
A sterilization apparatus comprising in combination: an openable and closeable housing for articles to be sterilized therein; support means to support said articles in said housing; means operable for introducing a heated sterilization fluid into said housing to sterilize said articles during a predetermined sterilization period; propulsion means operable for moving said fluid in a continuous flow near said articles in said housing; a cooling device at least partially disposed in said housing for cooling the articles during a cooling period following said sterilization period; and timing and controlling means for changing the direction of continuous flow of said fluid at time intervals that are short relative to the sterilization and cooling periods.
Claim 7
Dependent Claim
43 words
An apparatus according to claim 4, wherein said propulsion means is a fan having angularly adjustable blades of predetermined positions, said positions being controllable by said timing and controlling means for alternately changing said direction of the fluid during said short time intervals.
Claim 8
Dependent Claim
21 words
An apparatus as defined in claim 5, wherein said timing and controlling means includes a reversible driving motor for said fan.
Claim 9
Dependent Claim
24 words
An apparatus as defined in claim 4, further including a jacket surrounding said housing and defining an interspace between said jacket and said housing.
Claim 10
Dependent Claim
67 words
An apparatus as defined in claim 7, wherein said jacket includes an inlet and an outlet for introducing into said interspace first a heating medium and subsequently a cooling medium, whereby said medium-filled interspace is heatable to a predetermined sterilization temperature prior to the insertion of the articles into said interspace, and is coolable following sterilization of the articles to a predetermined discharge temperature of the articles.
Claim 11
Dependent Claim
156 words
A sterilization apparatus comprising in combination: an openable and closeable housing for articles to be sterilized therein; support means to support said articles in said housing at various regions; means operable for introducing a heated sterilization fluid into said housing to sterilize said articles during a predetermined sterilization period; propulsion means operable for moving said fluid in a continuous flow near said articles in said housing; a cooling device at least partially disposed in said housing for cooling the articles during a cooling period following said sterilization period; and timing and controlling means for changing the direction of continuous flow of said fluid, for dividing the flow of said fluid in said housing into at least two partial streams, and for periodically directing said partial stream to different, regions in said housing, whereby a relative high uniformity of heat transfer for sterilization between said fluid and the articles at said regions in said housing is attained.
Claim 12
Dependent Claim
156 words
A sterilization apparatus comprising in combination: an openable and closeable housing for articles to be sterilized therein; support means to support said articles in said housing at various regions; means operable for introducing a heated sterilization fluid into said housing to sterilize said articles during a predetermined sterilization period; propulsion means operable for moving said fluid in a continuous flow near said articles in said housing; a cooling device at least partially disposed in said housing for cooling the articles during a cooling period following said sterilization period; and timing and controlling means for changing the direction of continuous flow of said fluid, for dividing the flow of said fluid in said housing into at least two partial streams, and for periodically directing said partial stream to different, regions in said housing, whereby a relative high uniformity of heat transfer for sterilization between said fluid and the articles at said regions in said housing is attained.
Claim 13
Dependent Claim
49 words
An apparatus as defined in claim 9, wherein the timing and controlling means includes a plurality of valves successively arranged within the path of said partial streams, and wherein said timing and controlling means alternately opens and closes said valves to direct said partial streams towards said support means.
Claim 14
Dependent Claim
55 words
An apparatus as defined in claim 10, further including a plurality of temperature sensors respectively located at different regions in said housing for measuring temperature values, and a data processor coupled to said sensors and to said timing and controlling means for controlling said valves in response to the values measured by said temperature sensors.
References Cited (Backward Citations)
US2868616A
Cited
US2870024A
Cited
US3088180A
Cited
US3366442A
Cited
US3619126A
Cited
US3531300A
Cited
US3897818A
Cited
US3861872A
Cited
US3917450A
Cited
US4088444A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-03-11 | 1983-09-10 | 1984-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-03-11 | 1987-09-10 | 1988-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-03-11 | 1991-09-10 | 1992-03-11 | $7700.00 | Window Closed / Lapsed |