US4184978A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stable water in oil emulsion systems for cosmetic and pharmaceutical preparations
Assignee: CJ Patterson Co
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Filing: 1977-12-16
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Granted: 1980-01-22
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Expires: 1997-12-16
Abstract
Abstract A highly stable water in oil emulsion system for cosmetic or pharmaceutical preparations is provided wherein an unexpectedly high proportion of from about 70% to about 80% of an internal aqueous phase may be dispersed as globules usually of about one micron in a continuous external oleaginous phase by use of an emulsifier composition containing cooperatively effective amounts of (1) a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with a hydroxy carboxylic acid containing 2 to 4 carbon atoms (preferably calcium stearoyl-2-lactylate), and (2) a co-emulsifier compatible with emulsion (1) having an HLB value and present in a quantity to cause said emulsifier composition to have an effective HLB value within the range of about 4.6 to about 6.6. An emulsion may be produced using simple mechanical mixing techniques which has a static shelf life of at leat about six months at approximately 25° C.
Inventors
- 👤 James R. France
- 👤 Fred Baiocchi
- 👤 George A. Concar
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 14:52
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/02; A61K8/04; A61K8/06; A61K8/064; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/14; A61K47/24; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/39; A61K9/00; A61K9/0012; A61K9/0014; A61Q; A61Q19/00; C; C09; C09K; C09K23/00; C09K23/34; Y; Y10; Y10S; Y10S516/00; Y10S516/01; Y10S516/06
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
228 words
A stable water-in-oil emulsion system for cosmetic and pharmaceutical preparations comprising: a substantially continuous, external liquid oleaginous phase; a liquid non-homogenized internal aqueous phase comprising a sufficient amount of small aqueous globules dispersed in said external phase to present a collective quantity thereof initially of the order of about one micron in size at the time of dispersion and present within the range of from about 70% to about 80% on a weight to weight basis of the two phases; and an emulsifier composition combined with said phases which is capable of maintaining the water dispersed in the oleaginous phase for an extended period and comprising cooperatively effective amounts of at least (1) a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with a hydroxycarboxylic acid containing 2 to 4 carbon atoms and (2) a co-emulsifier non-reactive and compatible with emulsifier (1) said co-emulsifier being a derivative of a fatty acid or fatty alcohol which is different from the fatty acid radical of emulsifier (1) and having an HLB value and present in a quantity to (a) cause said emulsifier composition to have an effective HLB value within the range of about 4.6 to about 6.6 and (b) assure that the internal aqueous phase remains dispersed in said external phase for at least 6 months at approximately 25° C.
Claim 2
Dependent Claim
228 words
A stable water-in-oil emulsion system for cosmetic and pharmaceutical preparations comprising: a substantially continuous, external liquid oleaginous phase; a liquid non-homogenized internal aqueous phase comprising a sufficient amount of small aqueous globules dispersed in said external phase to present a collective quantity thereof initially of the order of about one micron in size at the time of dispersion and present within the range of from about 70% to about 80% on a weight to weight basis of the two phases; and an emulsifier composition combined with said phases which is capable of maintaining the water dispersed in the oleaginous phase for an extended period and comprising cooperatively effective amounts of at least (1) a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with a hydroxycarboxylic acid containing 2 to 4 carbon atoms and (2) a co-emulsifier non-reactive and compatible with emulsifier (1) said co-emulsifier being a derivative of a fatty acid or fatty alcohol which is different from the fatty acid radical of emulsifier (1) and having an HLB value and present in a quantity to (a) cause said emulsifier composition to have an effective HLB value within the range of about 4.6 to about 6.6 and (b) assure that the internal aqueous phase remains dispersed in said external phase for at least 6 months at approximately 25° C.
Claim 3
Dependent Claim
34 words
An emulsion system as set forth in claim 1 wherein emulsifier (1) is a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with lactic acid.
Claim 4
Dependent Claim
16 words
An emulsion system as set forth in claim 2 wherein said fatty acid is stearic acid.
Claim 5
Dependent Claim
15 words
An emulsion system as set forth in claim 2 wherein emulsifier (1) is calcium stearoyl-2-lactylate.
Claim 6
Dependent Claim
21 words
An emulsion system as set forth in claim 1 wherein said co-emulsifier is a derivative of oleic acid or oleyl alcohol.
Claim 7
Dependent Claim
26 words
An emulsion system as set forth in claim 5 wherein said co-emulsifier is a polyethylene glycol or polyethylene oxide derivative of oleic acid or oleyl alcohol.
Claim 8
Dependent Claim
21 words
An emulsion system as set forth in claim 1 wherein said co-emulsifier is a derivative of lauric acid or lauryl alcohol.
Claim 9
Dependent Claim
26 words
An emulsifier system as set forth in claim 7 wherein said co-emulsifier is a polyethylene glycol or polyethylene oxide derivative of lauric acid or lauryl alcohol.
Claim 10
Dependent Claim
19 words
An emulsion system as set forth in claim 1 wherein said co-emulsifier is a metal salt of isostearoyl lactylate.
Claim 11
Dependent Claim
28 words
An emulsion system as set forth in claim 1 wherein the ratio of emulsifier (1) to emulsifier (2) is within the range of about 50:50 to about 90:10.
Claim 12
Dependent Claim
18 words
An emulsion system as set forth in claim 1 wherein said aqueous phase contains a water soluble polyol.
Claim 13
Dependent Claim
18 words
An emulsion system as set forth in claim 1 wherein said aqueous phase contains a water soluble carbohydrate.
Claim 14
Dependent Claim
19 words
An emulsion system as set forth in claim 1 wherein said aqueous phase contains a water soluble inorganic salt.
Claim 15
Dependent Claim
17 words
An emulsion system as set forth in claim 1 wherein said oleaginous phase is an aliphatic oil.
Claim 16
Dependent Claim
15 words
An emulsion system as set forth in claim 14 wherein said oil is mineral oil.
Claim 17
Dependent Claim
14 words
An emulsion system as set forth in claim 15 wherein said oil is petrolatum.
Claim 18
Dependent Claim
17 words
An emulsion system as set forth in claim 1 wherein said oleaginous phase is a fatty alcohol.
Claim 19
Dependent Claim
16 words
An emulsion system as set forth in claim 17 wherein said fatty alcohol is cetyl alcohol.
Claim 20
Dependent Claim
17 words
An emulsion system as set forth in claim 17 wherein said fatty alcohol is a stearyl alcohol.
Claim 21
Dependent Claim
23 words
An emulsion system as set forth in claim 1 wherein said oleaginous phase includes a wax which is soluble in a liquid oil.
Claim 22
Dependent Claim
26 words
An emulsion system as set forth in claim 1 wherein is included at least about 4% on a weight to weight basis of said emulsifier composition.
Claim 23
Dependent Claim
25 words
An emulsion system as set forth in claim 1 wherein said aqueous phase includes from 73% to 81% water on a weight to weight basis.
Claim 24
Dependent Claim
53 words
An emulsion system as set forth in claim 1 wherein said emulsifier (1) is calcium stearoyl-2-lactylate and there is provided at least 81% water in said aqueous phase, about 9% to 15% oil in said oleaginous phase, and about 4% to 10% of said emulsifier composition, all on a weight to weight basis.
Claim 25
Dependent Claim
145 words
A stable water-in-oil emulsion system for cosmetic and pharmaceutical preparations comprising: a substantially continuous, external liquid oleaginous phase; a liquid non-homogenized internal aqueous phase comprising a sufficient amount of small aqueous globules dispersed in said external phase to present a collective quantity thereof initially of the order of about one micron in size at the range of from about 70% to about 80% on a weight to weight basis of the two phases; and an emulsifier composition combined with said phases which is capable of maintaining the water dispersed in the oleaginous phase for an extended period and comprising cooperatively effective amounts of at least (1) a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with a hydroxycarboxylic acid containing 2 to 4 carbon atoms and (2) a phosphated oleyl ether which has been substantially neutralized.
Claim 26
Dependent Claim
145 words
A stable water-in-oil emulsion system for cosmetic and pharmaceutical preparations comprising: a substantially continuous, external liquid oleaginous phase; a liquid non-homogenized internal aqueous phase comprising a sufficient amount of small aqueous globules dispersed in said external phase to present a collective quantity thereof initially of the order of about one micron in size at the range of from about 70% to about 80% on a weight to weight basis of the two phases; and an emulsifier composition combined with said phases which is capable of maintaining the water dispersed in the oleaginous phase for an extended period and comprising cooperatively effective amounts of at least (1) a di- or tri-valent salt of the esterification product of a C 10 to C 22 fatty acid with a hydroxycarboxylic acid containing 2 to 4 carbon atoms and (2) a phosphated oleyl ether which has been substantially neutralized.
Claim 27
Dependent Claim
15 words
An emulsion system as set forth in claim 24 wherein said oleyl ether is diethanolamine-oleth-3-phosphate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-01-21 | 1983-07-23 | 1984-01-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-01-21 | 1987-07-23 | 1988-01-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-01-21 | 1991-07-23 | 1992-01-22 | $7700.00 | Window Closed / Lapsed |