US4182653A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Mass transfer between fluids and apparatus therefor
Assignee: National Research Development Corp UK
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Filing: 1977-10-20
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Granted: 1980-01-08
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Expires: 1997-10-20
Abstract
Abstract The oxygenation and removal of carbon dioxide from blood by simultaneous mass transfer through a microporous membrane is improved by pulsing the flow of oxygenating gas over the membrane. This avoids the progressive reduction in carbon dioxide transfer rate which otherwise occurs with steady gas flow and allows such transfer rate to be maintained at an acceptable level.
Inventors
- 👤 Brian J. Bellhouse
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 19:38
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1698; A61M1/1621; A61M1/1631; A61M1/36; A61M1/3601; A61M1/3603; A61M1/3621; A61M1/3623; B; B01; B01D; B01D2313/00; B01D2313/24; B01D2313/243
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
97 words
A method of oxygenating blood and removing carbon dioxide therefrom, such method comprising flowing blood through a first conduit at least partly defined by a microporous membrane, flowing oxygenating gas through a second conduit adjacent to said first conduit at least partly defined by said membrane, and pulsing said gas as it flows through said second conduit, so that oxygen is transferred from said second to said first conduit and carbon dioxide from said first to said second conduit, the rate of carbon dioxide transfer being maintained at a higher level than otherwise occurs without said pulsing.
Claim 2
Independent Claim
97 words
A method of oxygenating blood and removing carbon dioxide therefrom, such method comprising flowing blood through a first conduit at least partly defined by a microporous membrane, flowing oxygenating gas through a second conduit adjacent to said first conduit at least partly defined by said membrane, and pulsing said gas as it flows through said second conduit, so that oxygen is transferred from said second to said first conduit and carbon dioxide from said first to said second conduit, the rate of carbon dioxide transfer being maintained at a higher level than otherwise occurs without said pulsing.
Claim 3
Dependent Claim
16 words
A method according to claim 1 wherein said pulsing is effected by interrupting said gas flow.
Claim 4
Dependent Claim
41 words
A method according to claim 1 wherein said pulsing is effected by applying a primary flow of said gas to said second conduit and superimposing, in parallel manner relative to said second conduit, a secondary pulsatile flow on said primary flow.
Claim 5
Dependent Claim
19 words
A method according to claim 1 wherein said gas is pulsed at a frequency of at least 30 cycles/minute.
Claim 6
Dependent Claim
23 words
A method according to claim 1 wherein said gas is pulsed at a frequency in the range from about 30 to 120 cycles/minute.
Claim 7
Dependent Claim
23 words
A method according to claim 1 wherein said gas is pulsed at a frequency in the range from about 50 to 100 cycles/minute.
Claim 8
Dependent Claim
35 words
A method according to claim 1 wherein said gas is pulsed to provide successive periods of relatively increased and decreased levels of gas supply which periods are in a ratio of up to about 4.
Claim 9
Dependent Claim
23 words
A process according to claim 1 wherein said gas is pulsed to produce pressure changes of about 30 mm Hg in said flow.
Claim 10
Dependent Claim
27 words
A process according to claim 1 wherein said gas is pulsed to produce pressure changes in the range from 20 to 30 mm Hg in said flow.
References Cited (Backward Citations)
US3332746A
Cited
US3484211A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-01-07 | 1983-07-09 | 1984-01-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-01-07 | 1987-07-09 | 1988-01-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-01-07 | 1991-07-09 | 1992-01-08 | $7700.00 | Window Closed / Lapsed |