US4181736A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Phenylacetic acid derivatives and therapeutic composition containing same
Assignee: Laboratoires Jacques Logeais SA
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Filing: 1978-11-21
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Granted: 1980-01-01
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Expires: 1998-11-21
Abstract
Abstract This invention relates to phenylacetic acid derivatives having the formula: ##STR1## in which A represents a grouping ##STR2## R, R 2 , R 3 and R 4 , which may be the same or different, represent each hydrogen or an alkyl group, and represents a single or double carbon-carbon bond; and their salts with inorganic and organic bases. Said compounds possess anti-inflammatory and analgesic activities that make them therapeutically useful, in particular for the treatment of rheumatic diseases and of local inflammations.
Inventors
- 👤 Jacques G. Maillard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 19:04
CPC Classifications
C; C07; C07C; C07C59/00; C07C59/40; C07C59/42; C07C59/54
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
22 words
A compound selected from the group consisting of 4(3-oxo-1-cyclohexenyl) phenyl acetic acid, 2[4(3-oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
22 words
A compound selected from the group consisting of 4(3-oxo-1-cyclohexenyl) phenyl acetic acid, 2[4(3-oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
10 words
4(3-Oxo-1-cyclohexenyl) phenyl acetic acid and the pharmaceutically acceptable salts thereof.
Claim 4
Dependent Claim
10 words
4(3-Oxo-1-cyclohexenyl) phenyl acetic acid and the pharmaceutically acceptable salts thereof.
Claim 5
Dependent Claim
10 words
2[4(3-Oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof.
Claim 6
Dependent Claim
10 words
2[4(3-Oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof.
Claim 7
Dependent Claim
43 words
Pharmaceutical compositions having analgesic and anti-inflammatory activity comprising an analgesic and anti-inflammatory effective amount of a compound selected from the group consisting of 4(3-oxo-1-cyclohexenyl) phenyl acetic acid, 2[4(3-oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof together with a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim
43 words
Pharmaceutical compositions having analgesic and anti-inflammatory activity comprising an analgesic and anti-inflammatory effective amount of a compound selected from the group consisting of 4(3-oxo-1-cyclohexenyl) phenyl acetic acid, 2[4(3-oxo-1-cyclohexenyl) phenyl] propionic acid and the pharmaceutically acceptable salts thereof together with a pharmaceutically acceptable carrier.
Claim 9
Dependent Claim
24 words
Pharmaceutical composition as claimed in claim 4, in unit dosage form, each unit dosage containing from 1 to 250 mg of said active ingredient.
Claim 10
Dependent Claim
66 words
Compounds of the formula: ##STR12## in which R, R 2 , R 3 and R 4 are selected from the group consisting of hydrogen and the alkyl groups; and their pharmaceutically acceptable salts; the number of carbon atoms in alkyl groups R and R 3 being from 1 to 4, and in R 2 and R 4 being from 1 to 8; Alk being lower alkyl.
Claim 11
Dependent Claim
66 words
Compounds of the formula: ##STR12## in which R, R 2 , R 3 and R 4 are selected from the group consisting of hydrogen and the alkyl groups; and their pharmaceutically acceptable salts; the number of carbon atoms in alkyl groups R and R 3 being from 1 to 4, and in R 2 and R 4 being from 1 to 8; Alk being lower alkyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-31 | 1983-07-02 | 1984-01-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-31 | 1987-07-02 | 1988-01-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-31 | 1991-07-02 | 1992-01-01 | $7700.00 | Window Closed / Lapsed |