US4181663A
Expired / Lapsed
US
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Selenium containing derivatives of proline and pipecolic acid
Assignee: ER Squibb and Sons LLC
•
Filing: 1979-01-29
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Granted: 1980-01-01
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Expires: 1999-01-29
Abstract
Abstract New selenium containing derivatives of proline and pipecolic acid which have the general formula ##STR1## are useful as hypotensive agents.
Inventors
- 👤 Rudiger D. Haugwitz
- 👤 Frank L. Weisenborn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:24
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/60
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
53 words
A compound of the formula ##STR13## wherein R is hydrogen, lower alkyl, phenyl or phenyl-lower alkyl; R 1 and R 3 each is hydrogen or lower alkyl; R 2 is hydrogen, lower alkyl, lower alkanoyl, benzoyl, phenyl-lower alkyl, phenyl or ##STR14## m is 1 or 2; and n is 0, 1 or 2.
Claim 2
Dependent Claim
53 words
A compound of the formula ##STR13## wherein R is hydrogen, lower alkyl, phenyl or phenyl-lower alkyl; R 1 and R 3 each is hydrogen or lower alkyl; R 2 is hydrogen, lower alkyl, lower alkanoyl, benzoyl, phenyl-lower alkyl, phenyl or ##STR14## m is 1 or 2; and n is 0, 1 or 2.
Claim 3
Dependent Claim
39 words
A compound as in claim 1 wherein R and R 1 each is hydrogen or lower alkyl; R 2 is hydrogen, lower alkanoyl, phenylmethyl, phenyl or ##STR15## R 3 is hydrogen; m and n each is 1 or 2.
Claim 4
Dependent Claim
10 words
A compound as in claim 1 wherein m is 1.
Claim 5
Dependent Claim
10 words
A compound as in claim 1 wherein m is 2.
Claim 6
Dependent Claim
10 words
A compound as in claim 1 wherein R is hydrogen.
Claim 7
Dependent Claim
11 words
A compound as in claim 1 wherein R 2 is hydrogen.
Claim 8
Dependent Claim
11 words
A compound as in claim 1 wherein R 2 is ##STR16##
Claim 9
Dependent Claim
27 words
A compound as in claim 1 wherein R, R 1 and R 3 each is hydrogen; R 2 is phenylmethyl; and m and n each is 1.
Claim 10
Dependent Claim
12 words
The L-form of the compound of claim 8 having the name 1-[1-oxo-3-[(phenylmethyl)selenyl]propyl]-L-proline.
Claim 11
Dependent Claim
23 words
A compound as in claim 7 wherein each R, R 1 and R 3 is hydrogen; and each m and n is 1.
Claim 12
Dependent Claim
12 words
The L-form of the compound of claim 10 having the name 1,1'-[diselenobis(3-oxo-3,1-propanediyl)]bis-L-proline.
Claim 13
Dependent Claim
26 words
A compound as in claim 7 wherein each R and R 3 is hydrogen; each R 1 is methyl; and each m and n is 1.
Claim 14
Dependent Claim
27 words
A compound as in claim 1 wherein R, R 2 and R 3 each is hydrogen; R 1 is methyl; and m and n each is 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-31 | 1983-07-02 | 1984-01-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-31 | 1987-07-02 | 1988-01-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-31 | 1991-07-02 | 1992-01-01 | $7700.00 | Window Closed / Lapsed |