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US4180566A Expired / Lapsed US ⏱️ 0.0 years remaining

Silica gel method of reducing blood lipid concentration

Assignee: WR Grace and Co
•
Filing: 1978-05-15
•
Granted: 1979-12-25
•
Expires: 1998-05-15
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Abstract

Abstract A method of reducing the lipid concentration in the blood of a patient comprises administering to the patient a lipid-lowering effective amount of silica gel.

Inventors

  • 👤 Milton E. Winyall
  • 👤 Kamal M. Abdo

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 00:12
CPC Classifications
A; A61; A61K; A61K33/00; A61P; A61P3/00; A61P3/06

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 43 words
A method of reducing the lipid concentration in the blood of a patient in need of same which comprises orally administering to the patient silica gel in a lipid reducing effective amount of at least about 0.2 grams per kilogram of body weight.
Claim 2
Independent Claim 43 words
A method of reducing the lipid concentration in the blood of a patient in need of same which comprises orally administering to the patient silica gel in a lipid reducing effective amount of at least about 0.2 grams per kilogram of body weight.
Claim 3
Dependent Claim 28 words
The method of claim 1 in which the silica gel is administered in an amount of from about 0.6 to about 1.4 grams per kilogram of body weight.
Claim 4
Dependent Claim 23 words
The method of claim 1 in which the silica gel is administered in a total daily amount of at least about 8 grams.
Claim 5
Dependent Claim 25 words
The method of claim 1 in which the silica gel is administered in a total daily amount of from about 8 to about 40 grams.
Claim 6
Dependent Claim 14 words
The method of claim 1 in which the silica gel is a silica hydrogel.
Claim 7
Dependent Claim 18 words
The method of claim 5 in which the silica hydrogel contains at least about 50 weight percent water.
Claim 8
Dependent Claim 20 words
The method of claim 5 in which the silica hydrogel contains from about 55 to about 75 weight percent water.
Claim 9
Independent Claim 50 words
A method of reducing the cholesterol concentration in the blood of a human patient in need of same which comprises orally administering to the patient a silica hydrogel containing at least about 50 weight percent water in a total daily lipid reducing effective amount of at least about 8 grams.
Claim 10
Independent Claim 50 words
A method of reducing the cholesterol concentration in the blood of a human patient in need of same which comprises orally administering to the patient a silica hydrogel containing at least about 50 weight percent water in a total daily lipid reducing effective amount of at least about 8 grams.
Claim 11
Dependent Claim 36 words
The method of claim 8 in which the silica hydrogel contains from about 50 to about 75 weight percent water and is administered in a total daily amount of from about 8 to about 40 grams.
Claim 12
Dependent Claim 23 words
The method of claim 5 in which the silica hydrogel is prepared by washing silica hydrogel particles with an aqueous ammonium hydroxide solution.
Claim 13
Dependent Claim 23 words
The method of claim 8 in which the silica hydrogel is prepared by washing silica hydrogel particles with an aqueous ammonium hydroxide solution.

References Cited (Backward Citations)

US4041153A Cited
US4064234A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-12-24 1983-06-25 1983-12-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-12-24 1987-06-25 1987-12-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-12-24 1991-06-25 1991-12-25 $7700.00 Window Closed / Lapsed

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