US4179569A
Expired / Lapsed
US
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N-(4-piperidinyl)-N-phenylamides
Assignee: Janssen Pharmaceutica NV
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Filing: 1977-12-19
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Granted: 1979-12-18
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Expires: 1997-12-19
Abstract
Abstract Novel N-(4-piperidinyl)-N-phenylamides and -carbamates having very potent analgesic activity, methods of preparing same and useful intermediates therefor.
Inventors
- 👤 Paul A. J. Janssen
- 👤 Georges H. P. Van Daele
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 21:31
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/30; C07D207/32; C07D207/33; C07D207/333; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/56; C07D211/58; C07D211/60; C07D211/62; C07D211/66; C07D333/00; C07D333/02; C07D333/04; C07D333/06; C07D333/14; C07D333/16
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
105 words
A compound selected from the group consisting of a piperidine derivative having the formula: ##STR102## and the stereochemical optical isomeric forms thereof, wherein: Z is a member selected from the group consisting of hydrogen, halo, lower alkyl, lower alkyloxy and trifluoromethyl; X is a member selected from the group consisting of hydrogen and methyl; L 2 is a member selected from the group consisting of alkyl having from 3 to 10 carbons and lower alkenyl; and R 13 is a carboxylate radical represented by the formula: ##STR103## wherein R 2 is a member selected from the group consisting of lower alkyl, lower alkenyl and phenylmethyl.
Claim 2
Dependent Claim
105 words
A compound selected from the group consisting of a piperidine derivative having the formula: ##STR102## and the stereochemical optical isomeric forms thereof, wherein: Z is a member selected from the group consisting of hydrogen, halo, lower alkyl, lower alkyloxy and trifluoromethyl; X is a member selected from the group consisting of hydrogen and methyl; L 2 is a member selected from the group consisting of alkyl having from 3 to 10 carbons and lower alkenyl; and R 13 is a carboxylate radical represented by the formula: ##STR103## wherein R 2 is a member selected from the group consisting of lower alkyl, lower alkenyl and phenylmethyl.
Claim 3
Dependent Claim
2 words
Ethyl 1-(1-methylethyl)-4-(phenylamino)-4-piperidinecarboxylate.
Claim 4
Dependent Claim
2 words
Ethyl 1-(1-methylethyl)-4-(phenylamino)-4-piperidinecarboxylate.
Claim 5
Dependent Claim
2 words
Methyl 1-(1-methylethyl)-4-phenylamino)-4-piperidinecarboxylate.
Claim 6
Dependent Claim
2 words
Methyl 1-(1-methylethyl)-4-phenylamino)-4-piperidinecarboxylate.
References Cited (Backward Citations)
US3655675A
Cited
US3998834A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-17 | 1983-06-18 | 1983-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-17 | 1987-06-18 | 1987-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-17 | 1991-06-18 | 1991-12-18 | $7700.00 | Window Closed / Lapsed |