US4177348A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Carbocyclic analogs of cytosine nucleosides
Assignee: Government of the United States of America
•
Filing: 1977-12-13
•
Granted: 1979-12-04
•
Expires: 1997-12-13
Abstract
Abstract Novel compounds are disclosed which are carbocyclic analogs of cytosine nucleosides in which the pentose moiety of the nucleoside is replaced by a cyclopentane ring. The novel compounds exhibit antiviral activity, and certain of them also exhibit antineoplastic activity against the L 1210 mouse leukemia test system.
Inventors
- 👤 Y. Fulmer Shealy
- 👤 C. Allen O'Dell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 02:24
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/32; C07D239/34; C07D239/36; C07D239/46; C07D239/47; C07D239/52; C07D239/54
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
45 words
A compound having a formula selected from the group consisting of ##STR7## wherein X and Y are hydrogen, hydroxy or benzolyoxy; R is hydrogen, lower alkyl or halogen; R 1 and R 2 are hydrogen or lower alkyl; and R 3 is hydrogen or acyl.
Claim 2
Dependent Claim
45 words
A compound having a formula selected from the group consisting of ##STR7## wherein X and Y are hydrogen, hydroxy or benzolyoxy; R is hydrogen, lower alkyl or halogen; R 1 and R 2 are hydrogen or lower alkyl; and R 3 is hydrogen or acyl.
Claim 3
Dependent Claim
28 words
The compound of claim 1, having the formula ##STR8## wherein X and Y are hydrogen or hydroxy; and R 1 and R 2 are hydrogen or lower alkyl.
Claim 4
Dependent Claim
13 words
The compound of claim 2, wherein R 1 and R 2 are hydrogen.
Claim 5
Dependent Claim
11 words
The compound of claim 3, wherein X and Y are hydroxy.
Claim 6
Dependent Claim
13 words
The compound of claim 3, wherein X is hydroxy and Y is hydrogen.
Claim 7
Dependent Claim
13 words
The compound of claim 3, wherein X is hydrogen and Y is hydroxy.
Claim 8
Dependent Claim
13 words
The compound of claim 2, wherein R 1 and R 2 are methyl.
Claim 9
Dependent Claim
11 words
The compound of claim 7, wherein X and Y are hydroxy.
Claim 10
Dependent Claim
13 words
The compound of claim 7, wherein X is hydroxy and Y is hydrogen.
Claim 11
Dependent Claim
13 words
The compound of claim 7, wherein X is hydrogen and Y is hydroxy.
Claim 12
Dependent Claim
28 words
The compound of claim 1, having the formula ##STR9## wherein X and Y are hydrogen or hydroxy; and R 1 and R 2 are hydrogen or lower alkyl.
Claim 13
Dependent Claim
13 words
The compound of claim 11, wherein R 1 and R 2 are hydrogen.
Claim 14
Dependent Claim
11 words
The compound of claim 12, wherein X and Y are hydroxy.
Claim 15
Dependent Claim
13 words
The compound of claim 12, wherein X is hydroxy and Y is hydrogen.
References Cited (Backward Citations)
US3040026A
Cited
DE2038807A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-03 | 1983-06-04 | 1983-12-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-03 | 1987-06-04 | 1987-12-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-03 | 1991-06-04 | 1991-12-04 | $7700.00 | Window Closed / Lapsed |