Hydroxy- and oxo-substituted α-benzylidenylcycloalkanes
Abstract
Abstract Hydroxy- and oxo-substituted α-benzylidenylcycloalkanes having the formula: ##STR1## Z 1 , Z 2 and Z 3 each denotes a methoxy group or Z 1 or Z 2 and Z 3 together denote a methylenedioxy group, and Z 3 is a hydrogen atom or chlorine atom, one of the symbols R 1 and R 2 denotes a hydrogen atom and the other denotes a hydroxyl group or, together the two denote an oxygen atom; R 3 denotes a hydrogen atom or a methyl group; R 4 denotes a hydrogen atom, a methyl group or an aminomethyl group, the amino group being a dimethylamino, diethylamino, morpholino, 4-methyl-piperazino or piperidino radical; or R 3 and R 4 together denote a piperonylidene group; R 5 denotes a hydrogen atom or a methyl group, and A forms, with the carbon atoms to which it is attached, a cyclopentane, cyclohexane, indane, tetrahydronaphthalene, perhydronaphthalene or piperidine structure and the pharmaceutically acceptable addition salts of the compounds containing an amino group. The compounds have pharmacological activity on the central nervous system.
Inventors
- 👤 Francois M. J. Vallet
Bibliographic Details
Claims Analysis
Total Claims: 6References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-03 | 1983-06-04 | 1983-12-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-03 | 1987-06-04 | 1987-12-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-03 | 1991-06-04 | 1991-12-04 | $7700.00 | Window Closed / Lapsed |