US4172457A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Plural component mixing system and method
Assignee: Baxter International Inc
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Filing: 1977-10-06
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Granted: 1979-10-30
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Expires: 1997-10-06
Abstract
Abstract A system for storing a dry powdered drug component and a liquid in separate containers and mixing them immediately prior to injection. The system has a hypodermic syringe with an axially slidable stopper, and the syringe is coupled to a rigid tubular housing with a low friction vacuum movable piston. Simple reciprocation of the syringe stopper with an attached plunger having a laterally extending thumb pad or other graspable slip resistant surface automatically reciprocates the housing's low friction piston and causes quick and complete turbulent mixing. There is no need to turn the device over and over in the operator's hands to alternately squeeze or push opposite ends of the device.
Inventors
- 👤 Pradip V. Choksi
- 👤 Kenneth R. Michael
- 👤 William H. Penny
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 12:22
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/14; A61J1/20; A61J1/2096; A61J1/2089; A61J1/2003; A61J1/202; A61J1/2041
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
69 words
A plural component mixing system comprising: a rigid tubular housing containing a first component and having a vacuum movable piston and a sealed outlet; a syringe with a rigid barrel containing a second component and having a manually retractable stopper capable of moving the housing's piston upon retraction of the stopper, which syringe has a sealed outlet; and coupling means for joining the outlets of the housing and syringe.
Claim 2
Dependent Claim
69 words
A plural component mixing system comprising: a rigid tubular housing containing a first component and having a vacuum movable piston and a sealed outlet; a syringe with a rigid barrel containing a second component and having a manually retractable stopper capable of moving the housing's piston upon retraction of the stopper, which syringe has a sealed outlet; and coupling means for joining the outlets of the housing and syringe.
Claim 3
Dependent Claim
45 words
A system as set forth in claim 1, wherein the housing and syringe are separate units each having means sealing their outlets, said housing and syringe have coupling structure adjacent their outlets for joining the housing and syringe immediately prior to mixing the two components.
Claim 4
Dependent Claim
23 words
A system as set forth in claim 1, wherein the housing and syringe are joined together and share a common outlet sealing means.
Claim 5
Dependent Claim
18 words
A system as set forth in claim 3, wherein the common outlet sealing means is a dislodgable barrier.
Claim 6
Dependent Claim
19 words
A system as set forth in claim 1, wherein the first component in the housing is a dry powder.
Claim 7
Dependent Claim
18 words
A system as set forth in claim 1, wherein the second component in the syringe is a liquid.
Claim 8
Dependent Claim
44 words
A system as set forth in claim 1, wherein the coupling means includes a needle adapter on the syringe barrel and a tubular sleeve on the housing, said sleeve fitting over the syringe barrel's needle adapter in a liquid-tight joint that is manually disconnectable.
Claim 9
Dependent Claim
50 words
A system as set forth in claim 7, wherein the syringe has a locking collar circumferentially disposed and spaced outwardly from the needle adapter, and there is internal locking structure on such collar; and the housing's sleeve has external retention means for engaging the internal locking structure of the collar.
Claim 10
Dependent Claim
19 words
A system as set forth in claim 1, wherein the housing is at least partially filled with a gas.
Claim 11
Dependent Claim
30 words
A system as set forth in claim 1, wherein the housing has a transverse rear wall behind the piston, and the housing has a vent positioned rearward of the stopper.
Claim 12
Dependent Claim
32 words
A system as set forth in claim 1, wherein the housing has a rear opening sealed by a separately formed closure, and there is a vent passage through or adjacent said closure.
Claim 13
Dependent Claim
39 words
A system as set forth in claim 1, wherein the housing has a coupling means at its outlet, and a supporting base structure on the housing that extends forwardly beyond the coupling means for supporting the housing during filling.
Claim 14
Dependent Claim
26 words
A system as set forth in claim 1, wherein the piston has a hollow section for aiding lateral resilience and low frictional drag on the housing.
Claim 15
Dependent Claim
90 words
A plural component mixing system comprising: a rigid tubular housing containing a first component and having a vacuum movable piston and a sealed outlet; a syringe with a rigid barrel containing a second component and having a manually retractable stopper connected to a handle means having a slip resistant area protruding from the rigid barrel, said stopper being capable of moving the housing's piston upon retraction of the stopper in the barrel; said syringe having a sealed outlet; and coupling means for joining the outlets of the housing and syringe.
Claim 16
Dependent Claim
90 words
A plural component mixing system comprising: a rigid tubular housing containing a first component and having a vacuum movable piston and a sealed outlet; a syringe with a rigid barrel containing a second component and having a manually retractable stopper connected to a handle means having a slip resistant area protruding from the rigid barrel, said stopper being capable of moving the housing's piston upon retraction of the stopper in the barrel; said syringe having a sealed outlet; and coupling means for joining the outlets of the housing and syringe.
Claim 17
Dependent Claim
23 words
A system as set forth in claim 14, wherein the slip resistant area of the handle means is a laterally extending thumb pad.
References Cited (Backward Citations)
US2660171A
Cited
US2724383A
Cited
US2726656A
Cited
US2798488A
Cited
US3163163A
Cited
US3397694A
Cited
US3376999A
Cited
US3494359A
Cited
US3685514A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-10-29 | 1983-04-30 | 1983-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-10-29 | 1987-04-30 | 1987-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-10-29 | 1991-04-30 | 1991-10-30 | $7700.00 | Window Closed / Lapsed |