Pharmacodynamically active indan derivatives

Abstract

Abstract The present invention relates to new pharmacodynamically active compounds of the general structure ##STR1## as well as the corresponding amine oxides, quarternary ammonium compounds and salts with physiologically acceptable acids. In formula I R 1 signifies hydrogen, halogen or alkoxy radicals having 1-3 carbon atoms, R 2 and R 3 signify alkyl radicals having 1-3 carbon atoms, which togetner with the carbon atom, to which they are connected, may form a ring, A either signifies a possibly lower alkyl substituted ethylene, trimethylene or tetramethylene group, in which case D is a group ##STR2## wherein R 4 and R 5 individually signify hydrogen or alkyl groups having 1-4 carbon atoms, or together with the nitrogen atom form a heterocyclic ring, which in addition to said nitrogen atom may contain an oxygen atom or possibly lower alkylated amino group, or A and B taken together signify a piperidino- or N-lower alkylpiperidino group, which is connected to an indene residue in 4-position, and the broken lines signify a double bond in either endo- or exo position.

Inventors

• 👤 Barbro K. Goransson-Dahlander
• 👤 Nils A. Jonsson
• 👤 Ferenc Merenyi

Bibliographic Details