US4154839A
Expired / Lapsed
US
⏱️ 0.0 years remaining
2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
Assignee: Bayer AG
•
Filing: 1978-05-08
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Granted: 1979-05-15
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Expires: 1998-05-08
Abstract
Abstract The isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate demonstrates the unique ability of increasing myocardial perfusion upon oral or intravenous administration. Methods of preparing the compound, its use in coronary conditions and pharmaceutical compositions for effecting that use are disclosed.
Inventors
- 👤 Egbert Wehinger
- 👤 Friedrich Bossert
- 👤 Arend Heise
- 👤 Stanislav Kazda
- 👤 Kurt Stoepel
- 👤 Wulf Vater
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 09:12
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/80; C07D211/84; C07D211/90
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
1 words
2,6-Dimethyl-3-carbomethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine.
Claim 2
Dependent Claim
1 words
2,6-Dimethyl-3-carbomethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine.
Claim 3
Dependent Claim
40 words
A pharmaceutical composition for increasing coronary perfusion which comprises the compound according to claim 1 in an amount sufficient upon enteral or parenteral administration to a human or other animal to increase coronary perfusion in combination with a pharmaceutical carrier.
Claim 4
Dependent Claim
14 words
A composition according to claim 2 wherein the composition is adapted for sublingual administration.
Claim 5
Dependent Claim
14 words
A composition according to claim 2 wherein the composition is adapted for intravenous administration.
Claim 6
Dependent Claim
36 words
The method of increasing coronary perfusion in humans and other animals which comprises administering to a human or other animal in need of increased coronary perfusion an effective amount of the compound according to claim 1.
References Cited (Backward Citations)
US3799934A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-14 | 1982-11-13 | 1983-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-14 | 1986-11-13 | 1987-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-14 | 1990-11-13 | 1991-05-15 | $7700.00 | Window Closed / Lapsed |