US4154827A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Inhibition of ADH-stimulated osmotic water flow and aldosterone-stimulated sodium transport
Assignee: University of Pennsylvania
•
Filing: 1977-12-15
•
Granted: 1979-05-15
•
Expires: 1997-12-15
Abstract
Abstract Inhibition of ADH-Stimulated osmotic water flow employing anhydro-7-chloro-6-demethyltetracycline (ADC) is disclosed. Also disclosed is the use of ADC in the inhibition of aldosterone-stimulated sodium transport.
Inventors
- 👤 Malcolm Cox
- 👤 Irwin Singer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 18:48
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/65
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
33 words
A method for the inhibition of anti-diuretic hormone-stimulated osmotic water flow in a mammal in need of such treatment, comprising treating said mammal with an effective amount of anhydro-7-chloro-6-demethyl tetracycline as the inhibitor.
Claim 2
Independent Claim
33 words
A method for the inhibition of anti-diuretic hormone-stimulated osmotic water flow in a mammal in need of such treatment, comprising treating said mammal with an effective amount of anhydro-7-chloro-6-demethyl tetracycline as the inhibitor.
Claim 3
Dependent Claim
16 words
The method of claim 1 wherein said anhydro-7-chloro-6-demethyltetracycline is employed at a concentration of 0.5 mg/ml.
Claim 4
Dependent Claim
17 words
The method of claim 2 wherein the method is carried out at a pH of about 7.3.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-14 | 1982-11-13 | 1983-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-14 | 1986-11-13 | 1987-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-14 | 1990-11-13 | 1991-05-15 | $7700.00 | Window Closed / Lapsed |