US4152413A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral vaccine for swine dysentery and method of use
Assignee: Chromalloy American Corp
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Filing: 1978-08-18
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Granted: 1979-05-01
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Expires: 1998-08-18
Abstract
Abstract An oral preparation for increasing the resistance of swine to swine dysentery infection comprises enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae. In the preferred method of use, the preparation is orally administered to swine in a plurality of doses providing at least 3 mg. of the cells per animal per dose.
Inventors
- 👤 Robert A. Goodnow
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:17
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/0225; Y; Y10; Y10S; Y10S424/00; Y10S424/825
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
52 words
An oral preparation for increasing the resistance of swine to swine dysentery infection, comprising enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines to release said cells for immunizing action.
Claim 2
Dependent Claim
52 words
An oral preparation for increasing the resistance of swine to swine dysentery infection, comprising enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines to release said cells for immunizing action.
Claim 3
Dependent Claim
21 words
The preparation of claim 1 in which said killed cells of Treponema hyodysenteriae are prepared from isolate B204 (ATCC No. 31287).
Claim 4
Dependent Claim
72 words
An oral preparation for increasing the resistance of swine to swine dysentery infection, comprising enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being substantially insoluble in water at a pH below 5.0 while being slowly soluble at a pH of 5.8 to 6.2, the coatings on said pellets requiring at least one hour to dissolve in water at 37° C. and pH 6.0.
Claim 5
Dependent Claim
72 words
An oral preparation for increasing the resistance of swine to swine dysentery infection, comprising enteric-coated orally-administrable pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being substantially insoluble in water at a pH below 5.0 while being slowly soluble at a pH of 5.8 to 6.2, the coatings on said pellets requiring at least one hour to dissolve in water at 37° C. and pH 6.0.
Claim 6
Independent Claim
77 words
The method of increasing the resistance of swine to swine dysentery infection, characterized by orally administering to swine while free of active swine dysentery infection a plurality of doses of enteric-coated pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines, and said doses providing at least 3 milligrams of said cells (dry basis) per animal per dose.
Claim 7
Independent Claim
77 words
The method of increasing the resistance of swine to swine dysentery infection, characterized by orally administering to swine while free of active swine dysentery infection a plurality of doses of enteric-coated pellets containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines, and said doses providing at least 3 milligrams of said cells (dry basis) per animal per dose.
Claim 8
Dependent Claim
21 words
The method of claim 4 in which said killed cells of Treponema hyodysenteriae are prepared from isolate B204 (ATCC No. 31287).
Claim 9
Independent Claim
103 words
The method of increasing the resistance of pigs to swine dysentery infection, said pigs being free of active swine dysentery infection but subject thereto, comprising preparing enteric-coated granules containing concentrated killed cells of a virulent isolate to Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines, mixing said granules with a finely-divided feed material for pigs, and feeding said mixture to the pigs at least once every 24 hours for a period of at least 5 days, each of said feedings providing at least 3 milligrams of said cells (dry basis) per animal.
Claim 10
Independent Claim
103 words
The method of increasing the resistance of pigs to swine dysentery infection, said pigs being free of active swine dysentery infection but subject thereto, comprising preparing enteric-coated granules containing concentrated killed cells of a virulent isolate to Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines, mixing said granules with a finely-divided feed material for pigs, and feeding said mixture to the pigs at least once every 24 hours for a period of at least 5 days, each of said feedings providing at least 3 milligrams of said cells (dry basis) per animal.
Claim 11
Dependent Claim
21 words
The method of claim 6 in which said killed cells of Treponema hyodysenteriae are prepared from isolate B204 (ATCC No. 31287).
Claim 12
Dependent Claim
53 words
The method of claim 6 in which said enteric coating is substantially insoluble in water at a pH below 5.0 while being slowly soluble in water at a pH of 5.8 to 6.2, the coatings on said granules requiring at least one hour to dissolve in water at 37° C. and pH 6.0.
Claim 13
Dependent Claim
21 words
The method of claim 8 in which said killed cells of Treponema hyodysenteriae are prepared from isolate B204 (ATCC No. 31287).
Claim 14
Dependent Claim
53 words
An antigenic premix containing vitamins and minerals for administration to growing pigs characterized by also containing enteric-coated granules containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines to release said cells for immunizing action.
Claim 15
Dependent Claim
53 words
An antigenic premix containing vitamins and minerals for administration to growing pigs characterized by also containing enteric-coated granules containing concentrated killed cells of a virulent isolate of Treponema hyodysenteriae, said enteric coating being resistant to dissolving in the swine stomach while dissolving in the swine intestines to release said cells for immunizing action.
Claim 16
Dependent Claim
22 words
The antigenic premix of claim 10 in which said killed cells of Treponema hyodysenteriae are prepared from isolate B204 (ATCC No. 31287).
Claim 17
Dependent Claim
55 words
The antigenic premix of claim 10 or claim 11 in which said enteric coating is substantially insoluble in water at a pH below 5.0 while being slowly soluble at a pH of 5.8 to 6.2, the coatings on said granules requiring at least one hour to dissolve in water at 37° C. and pH 6.0.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-30 | 1982-10-30 | 1983-05-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-30 | 1986-10-30 | 1987-05-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-30 | 1990-10-30 | 1991-05-01 | $7700.00 | Window Closed / Lapsed |