US4148885A
Expired / Lapsed
US
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Immunostimulant medicine
Assignee: Institut Merieux SA
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Filing: 1976-05-18
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Granted: 1979-04-10
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Expires: 1996-05-18
Abstract
Abstract Immunostimulant medicine comprises one or more sulfur compounds absent as a normal constituent in living beings, said compound comprising between about 16-40 percent sulfur in the molecule thereof, and an excipient therefor.
Inventors
- 👤 Gerard E. Renoux
- 👤 Micheline Renoux
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 04:29
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/04; A61K31/00; A61K31/16; A61K31/17; A61K31/175; A61K31/185; A61K31/19; A61K31/325; A61K31/33; A61K31/38; A61K31/395; A61K31/41; A61K31/415; A61K31/495; A61K31/505; A61K31/519; A61K31/52; A61K31/54; A61K39/00; A61K39/39
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium diethyldithiocarbamate and an excipient therefor, said sodium diethyldithiocarbamate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 2
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium diethyldithiocarbamate and an excipient therefor, said sodium diethyldithiocarbamate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 3
Dependent Claim
19 words
The process of claim 1 wherein said dosage administered comprises between 10 and 25 mg/kg of the receptor organism.
Claim 4
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium thiomalate and an excipient therefor, said sodium thiomalate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 5
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium thiomalate and an excipient therefor, said sodium thiomalate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 6
Dependent Claim
19 words
The process of claim 3 wherein said dosage administered comprises between 0.6 and 10 mg/kg of the receptor organism.
Claim 7
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium thiosulfate and an excipient therefor, said sodium thiosulfate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 8
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium thiosulfate and an excipient therefor, said sodium thiosulfate being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 9
Dependent Claim
19 words
The process of claim 5 wherein said dosage administered comprises at least about 1 mg/kg of the receptor organism.
Claim 10
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium metabisulfite and an excipient therefor, said sodium metabisulfite being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 11
Dependent Claim
80 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of sodium metabisulfite and an excipient therefor, said sodium metabisulfite being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 12
Dependent Claim
78 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of thiosemicarbazide and an excipient therefor, said thiosemicarbazide being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
Claim 13
Dependent Claim
78 words
A process for stimulating the immunity of a living organism comprising orally or subcutaneously administering to said organism in an amount effective to stimulate immunity an immunostimulant medicine consisting essentially of thiosemicarbazide and an excipient therefor, said thiosemicarbazide being administered at a dosage, relative to the weight of the receptor organism, which corresponds to a dosage which produces, in mice having received an injection of sheep red blood corpuscles, a stimulation index equal to or greater than 1.6.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-09 | 1982-10-09 | 1983-04-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-09 | 1986-10-09 | 1987-04-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-09 | 1990-10-09 | 1991-04-10 | $7700.00 | Window Closed / Lapsed |