US4147698A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-(Heterocyclicalkylamino)benzisothiazole-1,1-dioxides
Assignee: ER Squibb and Sons LLC
•
Filing: 1978-07-13
•
Granted: 1979-04-03
•
Expires: 1998-07-13
Abstract
Abstract Compounds having the formula ##STR1## wherein R 1 is hydrogen, halogen, alkyl alkoxy or nitro; R 2 is hydrogen, halogen or alkoxy; R 3 is an imidazol-4-yl or indol-3-yl; and n is 1,2,3 or 4, have antiinflammatory activity.
Inventors
- 👤 Peter C. Wade
- 👤 B. Richard Vogt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:37
CPC Classifications
C; C07; C07D; C07D275/00; C07D275/04; C07D275/06
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
69 words
A compound having the formula ##STR12## or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen, halogen, alkyl, alkoxy or nitro and R 2 is hydrogen, halogen or alkoxy, provided that if R 2 is other than hydrogen, R 1 and R 2 are the same; R 3 is ##STR13## wherein R 4 is hydrogen, halogen, alkyl, alkoxy or nitro, or ##STR14## and n is 1,2,3 or 4.
Claim 2
Dependent Claim
69 words
A compound having the formula ##STR12## or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen, halogen, alkyl, alkoxy or nitro and R 2 is hydrogen, halogen or alkoxy, provided that if R 2 is other than hydrogen, R 1 and R 2 are the same; R 3 is ##STR13## wherein R 4 is hydrogen, halogen, alkyl, alkoxy or nitro, or ##STR14## and n is 1,2,3 or 4.
Claim 3
Dependent Claim
12 words
A compound in accordance with claim 1 wherein R 3 is ##STR15##
Claim 4
Dependent Claim
12 words
A compound in accordance with claim 1 wherein R 3 is ##STR16##
Claim 5
Dependent Claim
12 words
The compound in accordance with claim 1 having the name N-[2-(1H-indol-3-yl)ethyl]-1,2-benzisothiazol-3-amine, 1,1-dioxide.
Claim 6
Dependent Claim
12 words
The compound in accordance with claim 1 having the name N-[2-(1H-imidazol-4-yl)ethyl]-1,2-benzisothiazol-3-amine, 1,1-dioxide.
Claim 7
Dependent Claim
14 words
The compound in accordance with claim 1 having the name N-[2-(1H-imidazol-4-yl)ethyl]-1,2-benzisothiazol-3-amine, 1,1-dioxide, hydrochloride (1:1).
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-02 | 1982-10-02 | 1983-04-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-02 | 1986-10-02 | 1987-04-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-02 | 1990-10-02 | 1991-04-03 | $7700.00 | Window Closed / Lapsed |