US4145546A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4-Pyrimidone compounds
Assignee: Smith Kline & French Laboratories Ltd
•
Filing: 1977-09-21
•
Granted: 1979-03-20
•
Expires: 1997-09-21
Abstract
Abstract The compounds are substituted isocytosines which are histamine H2-antagonists. Two specific compounds of the present invention are 2-[2-(5-methyl-4-imidazolylmethylthio)-ethylamino]-5-(3-methoxybenzyl) -4-pyrimidone and 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-benzyloxy-4-pyrimi done.
Inventors
- 👤 Thomas H. Brown
- 👤 Graham J. Durant
- 👤 John C. Emmett
- 👤 Charon R. Ganellin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 16:44
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/60; C07D239/66; C07D239/68; C07D239/56
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
22 words
A compound of the formula: ##STR11## in which Q is loweralkylthio or benzylthio and A is a 1,3-benzodioxolyl or a 2,3-dihydro-1,4-benzodioxinyl ring.
Claim 2
Dependent Claim
22 words
A compound of the formula: ##STR11## in which Q is loweralkylthio or benzylthio and A is a 1,3-benzodioxolyl or a 2,3-dihydro-1,4-benzodioxinyl ring.
Claim 3
Dependent Claim
10 words
A chemical intermediate of claim 1, said intermediate being 5-(5-(1,4-benzodioxolyl)methyl)-2-methylthio-4-pyrimidone.
Claim 4
Dependent Claim
10 words
A chemical intermediate of claim 1, said intermediate being 5-(6-(2,3-dihydro-1,4-benzodioxinyl)methyl)-2-methylthio-4-pyrimidone.
References Cited (Backward Citations)
BE814032A
Cited
US3932644A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-19 | 1982-09-18 | 1983-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-19 | 1986-09-18 | 1987-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-19 | 1990-09-18 | 1991-03-20 | $7700.00 | Window Closed / Lapsed |