US4145436A
Expired / Lapsed
US
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Antimicrobial compositions and method for using same
Assignee: Biosyn Inc
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Filing: 1977-11-07
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Granted: 1979-03-20
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Expires: 1997-11-07
Abstract
Abstract There are provided antimicrobial compositions of the low toxicity having enhanced activity against gram positive and gram negative bacteria as well as fungi or protozoa and consists essentially of: (a) an alkylimidazolium betaine in amounts up to 40 parts, by weight, and (b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine oxide, or an acrylamido t-amine oxide in amounts up to 40 parts, by weight. The composition exhibits skin degerming, cleansing, and deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.
Inventors
- 👤 Edwin B. Michaels
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:53
CPC Classifications
A; A61; A61Q; A61Q15/00; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/42; A61K8/49; A61K8/494; A61K8/4946; A61Q17/00; A61Q17/005
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
105 words
A broad spectrum, antimicrobial composition having both a pH ranging from about 4 to about 9.5 and low toxicity which consists essentially of: (a) from 0.1 to 40 parts, by weight, of a higher alkylimidazolium betaine, said betaine having the structure: ##STR3## where R is higher alkyl or mixed higher alkyl of from 10 to 18 carbon atoms, and (b) from 0.1 to 40 parts, by weight, of a higher alkyl-N, N-dimethylamine oxide, a higher alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl or mixed higher alkyl of from 10 to 18 carbon atoms.
Claim 2
Dependent Claim
105 words
A broad spectrum, antimicrobial composition having both a pH ranging from about 4 to about 9.5 and low toxicity which consists essentially of: (a) from 0.1 to 40 parts, by weight, of a higher alkylimidazolium betaine, said betaine having the structure: ##STR3## where R is higher alkyl or mixed higher alkyl of from 10 to 18 carbon atoms, and (b) from 0.1 to 40 parts, by weight, of a higher alkyl-N, N-dimethylamine oxide, a higher alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl or mixed higher alkyl of from 10 to 18 carbon atoms.
Claim 3
Dependent Claim
22 words
The composition according to claim 1, wherein from 1 to 20 parts of each of said betaine and amine oxide are present.
Claim 4
Dependent Claim
12 words
The composition according to claim 1, wherein the alkyl-N-betaine is 1-hydroxyethyl-1-carboxymethyl-2-cocoimidazolium betaine.
Claim 5
Dependent Claim
12 words
The composition according to claim 1, wherein the alkyl-N-betaine is 1-hydroxyethyl-1-carboxymethyl-2-stearylimidazolium betaine.
Claim 6
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is stearyl-N,N-dimethylamine oxide.
Claim 7
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is myristyl/palmitic-N,N-dimethylamine oxide.
Claim 8
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is coco-N,N-dimethylamine oxide.
Claim 9
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is stearyl-N,N-dihydroxyethylamine oxide.
Claim 10
Dependent Claim
32 words
The method for inhibiting the growth of microorganisms selected from the class consisting of bacteria, fungi and protozoa which comprises: applying thereto an antimicrobially effective amount of the composition of claim 1.
Claim 11
Dependent Claim
16 words
The method according to claim 9, wherein the growth of microorganisms is inhibited in incised wounds.
Claim 12
Dependent Claim
16 words
The method according to claim 9, wherein the growth of microorganisms is inhibited in pyogenic wounds.
References Cited (Backward Citations)
US3484523A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-19 | 1982-09-18 | 1983-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-19 | 1986-09-18 | 1987-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-19 | 1990-09-18 | 1991-03-20 | $7700.00 | Window Closed / Lapsed |