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US4144327A Expired / Lapsed US ⏱️ 0.0 years remaining

Antimicrobial composition comprising lytic enzymes from physarum and an antimycotic agent

Assignee: GD Searle LLC
•
Filing: 1978-03-20
•
Granted: 1979-03-13
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Expires: 1998-03-20
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Abstract

Abstract The present invention encompasses an antimicrobial composition comprising an extract of lytic enzymes from Physarum. These lytic enzymes are particularly effective antimycotic agents when used in conjunction with conventional antimycotic agents.

Inventors

  • 👤 David A. L. Davies
  • 👤 Anthony M. S. Pope

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 22:03
CPC Classifications
C; C12; C12N; C12N9/00; C12N9/14; C12N9/24; C12N9/2402; C12N9/2462; C12Y; C12Y302/00; C12Y302/01; C12Y302/01017; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 27 words
A method for treating fungal infections in animals comprising administering to an animal in need of antifungal treatment an effective amount of mycolytic enzymes extracted from Physarum.
Claim 2
Independent Claim 27 words
A method for treating fungal infections in animals comprising administering to an animal in need of antifungal treatment an effective amount of mycolytic enzymes extracted from Physarum.
Claim 3
Independent Claim 33 words
A method for treating fungal infections in animals comprising administering to an animal in need of anti-fungal treatment an effective amount of mycolytic enzymes extracts from Physarum in conjunction with an antimycotic agent.
Claim 4
Independent Claim 33 words
A method for treating fungal infections in animals comprising administering to an animal in need of anti-fungal treatment an effective amount of mycolytic enzymes extracts from Physarum in conjunction with an antimycotic agent.
Claim 5
Dependent Claim 37 words
A method according to claim 2 for treating fungal infections in animals comprising administering to an animal in need of anti-fungal treatment an effective amount of mycolytic enzymes extracted from Physarum in conjunction with Amphotericin-B or Nystatin.
Claim 6
Dependent Claim 37 words
A pharmaceutical composition suitable for combining with a pharmaceutically acceptable carrier comprising an effective amount of a sterile pyrogen free, lyophilised extract of lytic enzymes from Physarum in combination with an effective amount of an antimycotic agent.
Claim 7
Dependent Claim 37 words
A pharmaceutical composition suitable for combining with a pharmaceutically acceptable carrier comprising an effective amount of a sterile pyrogen free, lyophilised extract of lytic enzymes from Physarum in combination with an effective amount of an antimycotic agent.
Claim 8
Dependent Claim 16 words
A pharmaceutical composition, according to claim 4, wherein the antimycotic agent is Amphotericin-B, Nystatin, or 5-fluorocystosine.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-03-12 1982-09-11 1983-03-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-03-12 1986-09-11 1987-03-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-03-12 1990-09-11 1991-03-13 $7700.00 Window Closed / Lapsed

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