US4144320A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Aminoalcohols
Assignee: Pharmacia Animal Health Inc
•
Filing: 1977-04-12
•
Granted: 1979-03-13
•
Expires: 1997-04-12
Abstract
Abstract Aminoalcohol compounds and acid addition salts thereof, useful in the prevention and treatment of dental caries and periodontitis, are disclosed. Methods of preparing said derivatives, orally acceptable compositions containing said compounds, and a method of treatment therewith are also disclosed.
Inventors
- 👤 Sven E. H. Hernestam
- 👤 Nils A. Nilsson
- 👤 Lars-Olof Willard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 19:12
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/41; A61P; A61P1/00; A61P1/02; A61Q; A61Q11/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
5 words
A compound consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol.
Claim 2
Dependent Claim
5 words
A compound consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol.
Claim 3
Dependent Claim
62 words
An agent for use in the treatment of the oral cavity and on tooth surfaces to inhibit plaque formation consisting essentially from 0.1 to 5% of a substance active for plaque inhibition selected from the group consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol and pharmaceutically acceptable acid addition salts thereof in a pharmaceutically acceptable carrier conventionally used for cleansing and hygienic purposes in the oral cavity.
Claim 4
Dependent Claim
62 words
An agent for use in the treatment of the oral cavity and on tooth surfaces to inhibit plaque formation consisting essentially from 0.1 to 5% of a substance active for plaque inhibition selected from the group consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol and pharmaceutically acceptable acid addition salts thereof in a pharmaceutically acceptable carrier conventionally used for cleansing and hygienic purposes in the oral cavity.
Claim 5
Dependent Claim
31 words
An agent according to claim 2, wherein said active substance is in the form of a solution in a carrier conventionally used for cleansing and hygienic purposes in the oral cavity.
Claim 6
Dependent Claim
31 words
An agent according to claim 2, wherein said active substance is in the form of a suspension in a carrier conventionally used for cleansing and hygienic purposes in the oral cavity.
Claim 7
Dependent Claim
30 words
An agent according to claim 2, wherein said active substance is in the solid form admixed with a carrier conventionally used for cleansing and hygienic purposes in the oral cavity.
Claim 8
Dependent Claim
35 words
An agent according to claim 2, wherein said carrier for cleansing and hygienic purposes in the oral cavity is selected from the group consisting of tooth paste, mouth rinse liquid, chewing gum and chewable tablets.
Claim 9
Independent Claim
42 words
A method of treatment for inhibiting plaque of the oral cavity and on tooth surfaces which comprises using an effective amount of a substance active in plaque inhibition selected from the group consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol and pharmaceutically acceptable acid addition salts thereof.
Claim 10
Independent Claim
42 words
A method of treatment for inhibiting plaque of the oral cavity and on tooth surfaces which comprises using an effective amount of a substance active in plaque inhibition selected from the group consisting of N-n-butyl-N-cetyl-6-amino-1-hexanol and pharmaceutically acceptable acid addition salts thereof.
References Cited (Backward Citations)
US1919298A
Cited
US2383564A
Cited
US2562488A
Cited
US2689170A
Cited
US3591679A
Cited
US4059624A
Cited
US3862308A
Cited
US3932605A
Cited
US3998945A
Cited
US4006218A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-12 | 1982-09-11 | 1983-03-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-12 | 1986-09-11 | 1987-03-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-12 | 1990-09-11 | 1991-03-13 | $7700.00 | Window Closed / Lapsed |