Patent EP0823813A2 successfully refreshed from Google Patents.
US4140777A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cerebral vasodilating 6-substituted vincamines
Assignee: Individual
•
Filing: 1977-05-31
•
Granted: 1979-02-20
•
Expires: 1997-05-31
Abstract
Abstract The invention relates to novel derivatives of vincamine and apovincamine having the formula ##STR1## WHICH ARE ENDOWED WITH ANALOGOUS PROPERTIES AS THE VINCAMINE AND APOVINCAMINE AS WELL AS WITH AN EXTENDED EFFECT. The invention relates also to the methods for the preparation of the above derivatives.
Inventors
- 👤 Davide Vegezzi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:13
CPC Classifications
C; C07; C07D; C07D461/00; A; A61; A61P; A61P9/00; A61P9/08
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
56 words
A vincamine compound having the formula: ##STR5## wherein R is --OH, ═O, R 1 is OH or is absent and R 2 is COOCH 3 , CH 2 OH, a double bond in the Δ 16 , 17 position being present when R 1 is absent or R 1 + R 2 R 2 = ═O.
Claim 2
Dependent Claim
56 words
A vincamine compound having the formula: ##STR5## wherein R is --OH, ═O, R 1 is OH or is absent and R 2 is COOCH 3 , CH 2 OH, a double bond in the Δ 16 , 17 position being present when R 1 is absent or R 1 + R 2 R 2 = ═O.
Claim 3
Dependent Claim
9 words
The compound according to claim 1, which is 6-ketovincamine.
Claim 4
Dependent Claim
9 words
The compound according to claim 1, which is 6-hydroxyvincamine.
Claim 5
Dependent Claim
9 words
The compound according to claim 1, which is 6-ketovincaminol.
Claim 6
Dependent Claim
9 words
The compound according to claim 1, which is 6-ketovincamone.
Claim 7
Dependent Claim
9 words
The compound according to claim 1, which is 6-keto-16-epivincamine.
Claim 8
Dependent Claim
9 words
The compound according to claim 1, which is 6-ketoapovincamine.
Claim 9
Dependent Claim
22 words
A cerebral vasodilating composition, comprising 40-160 milligrams daily dosage of a vincamine derivative according to claim 1 in a pharmaceutically acceptable excipient.
References Cited (Backward Citations)
FR2175317A5
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-02-19 | 1982-08-21 | 1983-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-02-19 | 1986-08-21 | 1987-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-02-19 | 1990-08-21 | 1991-02-20 | $7700.00 | Window Closed / Lapsed |