US4139639A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Fixation of APM in chewing gum
Assignee: General Foods Corp
•
Filing: 1977-10-28
•
Granted: 1979-02-13
•
Expires: 1997-10-28
Abstract
Abstract This invention relates to a product and process in which L-aspartyl-L-phenylalanine methyl ester is fixed in gum Arabic and/or the reaction product of a compound containing a polyvalent metallic ion, with an ungelatinized starch acid-ester of a substituted dicarboxylic acid whereby the decomposition rate of the L-aspartyl-L-phenylalanine methyl ester when employed in a chewing gum system is greatly reduced.
Inventors
- 👤 Bernard J. Bahoshy
- 👤 Robert E. Klose
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:45
CPC Classifications
A; A23; A23G; A23G4/00; A23G4/06; A23G4/10; A23G4/18; A23G4/20
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
195 words
A chewing gum composition which comprises gum base, flavor, a bulking agent and L-aspartyl-L-phenylalanine methyl ester wherein the L-aspartyl-L-phenylalanine methyl ester is fixed in an encapsulating agent composition and the ratio of encapsulating agent composition to L-aspartyl-L-phenylalanine methyl ester is between about 10:1 to about 2:1 and the encapsulating agent composition consists of gum arabic and the reaction product of a compound containing a polyvalent metallic ion, with an ungelatinized starch acid-ester of a substituted dicarboxylic acid, such starch acid-esters represented diagrammatically by the following formula: ##STR3## where R is a radical selected from the class consisting of dimethylene and trimethylene radicals, and R 1 is a hydrocarbon constituent selected from the class consisting of alkyl, alkenyl, aralkyl or aralkenyl groups, the above-described ungelatinized starch acid-esters are prepared by reacting an ungelatinized starch, in an alkaline medium, with a substituted cyclic dicarboxylic acid anhydride having the following formula: ##STR4## where R and R 1 represent the same substituent groups as are listed above for those same symbols, substituted cyclic dicarboxylic anhydrides falling within this formula are the substituted succinic and glutaric acid anhydrides whereby the conversion of L-aspartyl-L-phenylalanine methyl ester to diketopiperazine is greatly reduced.
Claim 2
Dependent Claim
195 words
A chewing gum composition which comprises gum base, flavor, a bulking agent and L-aspartyl-L-phenylalanine methyl ester wherein the L-aspartyl-L-phenylalanine methyl ester is fixed in an encapsulating agent composition and the ratio of encapsulating agent composition to L-aspartyl-L-phenylalanine methyl ester is between about 10:1 to about 2:1 and the encapsulating agent composition consists of gum arabic and the reaction product of a compound containing a polyvalent metallic ion, with an ungelatinized starch acid-ester of a substituted dicarboxylic acid, such starch acid-esters represented diagrammatically by the following formula: ##STR3## where R is a radical selected from the class consisting of dimethylene and trimethylene radicals, and R 1 is a hydrocarbon constituent selected from the class consisting of alkyl, alkenyl, aralkyl or aralkenyl groups, the above-described ungelatinized starch acid-esters are prepared by reacting an ungelatinized starch, in an alkaline medium, with a substituted cyclic dicarboxylic acid anhydride having the following formula: ##STR4## where R and R 1 represent the same substituent groups as are listed above for those same symbols, substituted cyclic dicarboxylic anhydrides falling within this formula are the substituted succinic and glutaric acid anhydrides whereby the conversion of L-aspartyl-L-phenylalanine methyl ester to diketopiperazine is greatly reduced.
Claim 3
Dependent Claim
11 words
The composition of claim 1 wherein the bulking agent is sugar.
Claim 4
Dependent Claim
25 words
The composition of claim 1 wherein the bulking agent comprises a sugar alcohol selected from the group consisting of sorbitol, mannitol, xylitol and mixtures thereof.
Claim 5
Dependent Claim
162 words
The composition of claim 3 wherein the L-aspartyl-L-phenylalanine methyl ester is fixed by co-drying an aqueous solution of L-aspartyl-L-phenylalanine methyl ester with an aqueous solution of an encapsulating agent composition consisting of gum arabic and the reaction product of a compound containing a polyvalent metallic ion, with an ungelatinized starch acid-ester of a substituted dicarboxylic acid, such starch acid-esters represented diagrammatically by the following formula: ##STR5## where R is a radical selected from the class consisting of dimethylene and trimethylene radicals, and R 1 is a hydrocarbon constituent selected from the class consisting of alkyl, alkenyl, aralkyl or aralkenyl groups, the above-described ungelatinized starch acid-esters are prepared by reacting an ungelatinized starch, in an alkaline medium, with a substituted cyclic dicarboxylic acid anhydride having the following formula: ##STR6## where R and R 1 represent the same substituent groups as are listed above for those same symbols, substituted cyclic dicarboxylic anhydrides falling within this formula are the substituted succinic and glutaric acid anhydrides.
Claim 6
Dependent Claim
13 words
The composition of claim 4 wherein the drying method employed is spray drying.
Claim 7
Dependent Claim
18 words
The composition of claim 5 wherein the aqueous solution enters the spray dryer via a rotating disc nozzle.
Claim 8
Dependent Claim
23 words
The composition of claim 1 wherein the ratio of L-aspartyl-L-phenylalanine methyl ester to the co-drying ingredients is between about 5:1 to about 3:1.
Claim 9
Dependent Claim
58 words
A chewing gum composition which comprises gum base, flavor, a bulking agent and L-aspartyl-L-phenylalanine methyl ester wherein the L-aspartyl-L-phenylalanine methyl ester is fixed in the encapsulating agent gum arabic and the ratio of gum arabic to L-aspartyl-L-phenylalanine methyl ester is between about 10:1 to about 2:1 whereby the conversion of L-aspartyl-L-phenylalanine methyl ester to diketopiperazine is greatly reduced.
Claim 10
Dependent Claim
58 words
A chewing gum composition which comprises gum base, flavor, a bulking agent and L-aspartyl-L-phenylalanine methyl ester wherein the L-aspartyl-L-phenylalanine methyl ester is fixed in the encapsulating agent gum arabic and the ratio of gum arabic to L-aspartyl-L-phenylalanine methyl ester is between about 10:1 to about 2:1 whereby the conversion of L-aspartyl-L-phenylalanine methyl ester to diketopiperazine is greatly reduced.
Claim 11
Dependent Claim
11 words
The composition of claim 8 wherein the bulking agent is sugar.
Claim 12
Dependent Claim
25 words
The composition of claim 9 wherein the bulking agent comprises a sugar alcohol selected from the group consisting of sorbitol, mannitol, xylitol and mixtures thereof.
Claim 13
Dependent Claim
31 words
The composition of claim 10 wherein the laspartyl-L-phenylalanine methyl ester is fixed by co-drying an aqueous solution of L-aspartyl-L-phenylalanine methyl ester with an aqueous solution of the encapsulating agent gum Arabic.
Claim 14
Dependent Claim
13 words
The composition of claim 11 wherein the drying method employed is spray drying.
Claim 15
Dependent Claim
18 words
The composition of claim 12 wherein the aqueous solution enters the spray dryer via a rotating disc nozzle.
Claim 16
Dependent Claim
23 words
The composition of claim 8 wherein the ratio of L-aspartyl-L-phenylalanine methyl ester to the co-drying ingredients is between about 5:1 to about 3:1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-02-12 | 1982-08-14 | 1983-02-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-02-12 | 1986-08-14 | 1987-02-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-02-12 | 1990-08-14 | 1991-02-13 | $7700.00 | Window Closed / Lapsed |