US4131675A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of combinations of L-DOPA with trazodone and L-DOPA with etoperidone in Parkinsonism
Assignee: Angelini Acraf SpA
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Filing: 1978-02-09
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Granted: 1978-12-26
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Expires: 1998-02-09
Abstract
Abstract A combination of trazodone or etoperidone with L-DOPA is used in the treatment of Parkinsonism by oral administration to a patient.
Inventors
- 👤 Bruno Silvestrini
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 21:37
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/496
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
64 words
A method of treatment of Parkinsonism comprising administering to a patient a combination of trazodone with L-DOPA or etoperidone with L-DOPA at a daily oral dose of 100 to 200 mg of trazodone or etoperidone and a daily dose of 2 to 4 g of L-DOPA substantially in a ratio of 1 part of trazodone or etoperidone for 12 to 25 parts of L-DOPA.
Claim 2
Independent Claim
64 words
A method of treatment of Parkinsonism comprising administering to a patient a combination of trazodone with L-DOPA or etoperidone with L-DOPA at a daily oral dose of 100 to 200 mg of trazodone or etoperidone and a daily dose of 2 to 4 g of L-DOPA substantially in a ratio of 1 part of trazodone or etoperidone for 12 to 25 parts of L-DOPA.
Claim 3
Dependent Claim
36 words
A method of treatment according to claim 1, wherein said treatment is carried out at a ratio of about 12 parts to about 25 parts of L-DOPA for every part of trazodone or etoperidone being administered.
Claim 4
Dependent Claim
41 words
A method of treatment according to claim 1, wherein said L-DOPA is administered separately from said trazodone or from said etoperidone for said combination treatment or wherein said L-DOPA is administered together with said trazodone or etoperidone for said combination treatment.
Claim 5
Dependent Claim
17 words
A treatment according to claim 3, wherein the combined drugs are substantially in the ratio of 1:20.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-12-25 | 1982-06-26 | 1982-12-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-12-25 | 1986-06-26 | 1986-12-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-12-25 | 1990-06-26 | 1990-12-26 | $7700.00 | Window Closed / Lapsed |