US4130637A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti-plaque agents
Assignee: Colgate Palmolive Co
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Filing: 1977-10-03
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Granted: 1978-12-19
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Expires: 1997-10-03
Abstract
Abstract Novel betaine compounds derived from higher alkyl dimethyl carboxylic acid quaternary ammonium compounds; the process of preparing said betaines; and compositions containing an effective antimicrobial amount of said betaines admixed with a pharmaceutical carrier. These compounds are effective in controlling dental plaque without producing an esthetically unacceptable discoloration of tooth surfaces.
Inventors
- 👤 Robert A. Bauman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 09:09
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/44; A61Q; A61Q11/00; Y; Y10; Y10S; Y10S436/00; Y10S436/907
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
47 words
A non-staining, anti-plaque oral composition containing an effective antimicrobial amount of a betaine represented by the general formula: RN.sup.+ (CH.sub.3).sub.2 (CH.sub.2).sub.n COO.sup.-, wherein R is an alkyl group containing 12 to 18 carbon atoms and n is an integer from 8 to 12, in an oral vehicle.
Claim 2
Dependent Claim
47 words
A non-staining, anti-plaque oral composition containing an effective antimicrobial amount of a betaine represented by the general formula: RN.sup.+ (CH.sub.3).sub.2 (CH.sub.2).sub.n COO.sup.-, wherein R is an alkyl group containing 12 to 18 carbon atoms and n is an integer from 8 to 12, in an oral vehicle.
Claim 3
Dependent Claim
15 words
A composition in accordance with claim 1, wherein the betaine is -N-(10-Carboxydecyl)-N,N-dimethyltetradecanaminium hydroxide, inner salt.
Claim 4
Dependent Claim
15 words
A composition in accordance with claim 1, wherein the betaine is -N-(10-Carboxydecyl)-N,N-dimethylhexadecanaminium hydroxide, inner salt.
Claim 5
Dependent Claim
17 words
A composition in accordance with claim 1, wherein the composition has a pH of 4 to 9.
Claim 6
Dependent Claim
26 words
A composition in accordance with claim 4, wherein the betaine exists as a mixture of at least 50% betaine and its corresponding carboxylic acid quaternary compound.
Claim 7
Dependent Claim
25 words
A composition in accordance with claim 5, wherein the betaine constitutes about 0.025 to 10% by weight of the compound in an inert pharmaceutical carrier.
Claim 8
Dependent Claim
30 words
A composition in accordance with claim 5, wherein the betaine constitutes about 0.05 to 5.0% by weight in a dental vehicle containing about 20-95% by weight of water-insoluble polishing material.
Claim 9
Dependent Claim
32 words
A composition in accordance with claim 5, wherein the betaine constitutes about 0.025 to 10% by weight in a dental vehicle containing about 20-99% by weight of an aqueous lower aliphatic alcohol.
Claim 10
Dependent Claim
20 words
A composition in accordance with claim 5, wherein the oral vehicle contains about 0.2-3.0% by weight of a non-ionic surfactant.
References Cited (Backward Citations)
US3617439A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-12-18 | 1982-06-19 | 1982-12-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-12-18 | 1986-06-19 | 1986-12-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-12-18 | 1990-06-19 | 1990-12-19 | $7700.00 | Window Closed / Lapsed |