US4130582A
Expired / Lapsed
US
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Preparation of phenolic ethylenediaminepolycarboxylic acids
Assignee: Novartis Corp
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Filing: 1977-04-19
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Granted: 1978-12-19
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Expires: 1997-04-19
Abstract
Abstract A process for the preparation of phenolic ethylenediamine polycarboxylic acids in predominantly the ortho isomeric form which comprises reacting a phenol compound, ethylenediamine, glyoxylic acid and a base, said phenol compound functioning both as a reactant and as the sole solvent for the reaction system. The product can then be isolated or directly reacted with an iron salt to form the corresponding iron chelate.
Inventors
- 👤 Harris E. Petree
- 👤 Hal L. Myatt
- 👤 Alex M. Jelenevsky
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 11:20
CPC Classifications
C; C07; C07C; C07C227/00; C07C227/04; C07C227/10; C07C233/00; C07C233/01; C07C233/12; C07C227/14; C07C227/18
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
68 words
A process for the preparation of ethylene-bis(α-imino-hydroxyphenylacetic acid) wherein a major portion thereof is an orto isomeric form, said process comprising reacting, at a temperature of from about 45° to 80° C., phenol with ethylenediamine, glyoxylic acid and a base; said phenol, ethylenediamine, glyoxylic acid and base being present in a molar ratio of 3 to 20, 0.5 to b 0.55, 0.95 to 1.25 and 0.75 to 1.25.
Claim 2
Dependent Claim
68 words
A process for the preparation of ethylene-bis(α-imino-hydroxyphenylacetic acid) wherein a major portion thereof is an orto isomeric form, said process comprising reacting, at a temperature of from about 45° to 80° C., phenol with ethylenediamine, glyoxylic acid and a base; said phenol, ethylenediamine, glyoxylic acid and base being present in a molar ratio of 3 to 20, 0.5 to b 0.55, 0.95 to 1.25 and 0.75 to 1.25.
Claim 3
Dependent Claim
11 words
The process of claim 1, wherein said molar ratio is 13:0.5:1:1.
Claim 4
Dependent Claim
24 words
The process of claim 1, wherein said reaction is conducted at a temperature of 70°-75° C. for a period of two to four hours.
Claim 5
Dependent Claim
19 words
The process of claim 1, wherein greater than about 85% of said product is in the ortho isomeric form.
References Cited (Backward Citations)
US2824128A
Cited
US3825592A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-12-18 | 1982-06-19 | 1982-12-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-12-18 | 1986-06-19 | 1986-12-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-12-18 | 1990-06-19 | 1990-12-19 | $7700.00 | Window Closed / Lapsed |