US4123614A
Expired / Lapsed
US
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Novel assay reagents
Assignee: Syntex USA LLC
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Filing: 1976-10-18
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Granted: 1978-10-31
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Expires: 1996-10-18
Abstract
Abstract The present invention relates to novel assay reagents, their composition, methods of preparation, and use in the detection and measurement of various biological systems and/or components, e.g. enzymes, antibodies, antigens, and periodate concentration. This invention in its basic form utilizes a class of compounds having, inter alia., a backbone chain, an indicator group, and vicinal oxidizable groups.
Inventors
- 👤 David H. Rammler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:30
CPC Classifications
C; C07; C07D; C07D303/00; C07D303/02; C07D303/12; C07D303/18; C07D303/20; C07D303/22; C07C; C07C205/00; C07C205/27; C07C205/35; C07C205/36; C07C205/37; C07C305/00; C07C305/02; C07C305/04; C07C305/10; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/091; C07F9/22; C07F9/222; C12; C12Q; C12Q1/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/535; Y; Y10; Y10S; Y10S436/00; Y10S436/811; Y10S436/815; Y10S436/817; Y10S436/818; Y10S436/82; Y10S436/826
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
77 words
A reagent useful for enzyme measurements which is a compound selected from those represented by the following formula: ##STR18## wherein, R 1 is 4-nitrophenyloxy or 2,4-dinitrophenyloxy; n is 1; R 2 is hydrogen; and R 10 and R 11 each is independently hydroxy or a carboxylic ester of the formula ##STR19## wherein R 3 is alkyl of one to eighteen carbon atoms, provided that at least one of R 10 and R 11 is a carboxylic ester.
Claim 2
Dependent Claim
77 words
A reagent useful for enzyme measurements which is a compound selected from those represented by the following formula: ##STR18## wherein, R 1 is 4-nitrophenyloxy or 2,4-dinitrophenyloxy; n is 1; R 2 is hydrogen; and R 10 and R 11 each is independently hydroxy or a carboxylic ester of the formula ##STR19## wherein R 3 is alkyl of one to eighteen carbon atoms, provided that at least one of R 10 and R 11 is a carboxylic ester.
Claim 3
Dependent Claim
12 words
The compound according to claim 1 wherein said carboxylic ester is acetoxy.
Claim 4
Dependent Claim
19 words
The compound according to claim 2 wherein R 11 is acetoxy, R 10 is hydroxy, and n is 1.
References Cited (Backward Citations)
US2291527A
Cited
US3419620A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-30 | 1982-05-01 | 1982-10-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-30 | 1986-05-01 | 1986-10-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-30 | 1990-05-01 | 1990-10-31 | $7700.00 | Window Closed / Lapsed |