US4123546A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antidepressant compounds
Assignee: EIDP Inc
•
Filing: 1977-07-01
•
Granted: 1978-10-31
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Expires: 1997-07-01
Abstract
Abstract Antidepressant compounds such as 2-[(4b,4c-dihydro-8bH-azirino[2,1,3-cd]dibenzo[a,f]pyrrolizin-8b-yl)oxy]ethyl-N,N-dimethylamine useful for alleviating depression in mammals.
Inventors
- 👤 Michael J. Haire
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 11:06
CPC Classifications
C; C07; C07D; C07D451/00; C07D203/00; C07D203/26
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
52 words
A compound of the formula ##STR20## where X is H, F, Cl, Br, C 1-4 alkyl, C 1-4 alkoxy, CF 3 or C 1-4 alkyl sulfonyl; Z is C 2 -C 3 alkylene; and R 1 and R 2 independently are H, C 1-4 alkyl; or its pharmaceutically suitable acid addition salt.
Claim 2
Dependent Claim
52 words
A compound of the formula ##STR20## where X is H, F, Cl, Br, C 1-4 alkyl, C 1-4 alkoxy, CF 3 or C 1-4 alkyl sulfonyl; Z is C 2 -C 3 alkylene; and R 1 and R 2 independently are H, C 1-4 alkyl; or its pharmaceutically suitable acid addition salt.
Claim 3
Dependent Claim
18 words
A compound of claim 1 where R 1 and R 2 independently are H or CH 3 .
Claim 4
Dependent Claim
25 words
A compound of claim 1 wherein X is H, Z is ethylene, and R 1 and R 2 independently are H or CH 3 .
Claim 5
Dependent Claim
13 words
The compound of claim 3 where R 1 and R 2 are H.
Claim 6
Dependent Claim
17 words
The compound of claim 3 where R 1 is H and R 2 is CH 3 .
Claim 7
Dependent Claim
15 words
The compound of claim 3 where R 1 and R 2 are CH 3 .
Claim 8
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 1.
Claim 9
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 2.
Claim 10
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 3.
Claim 11
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 4.
Claim 12
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 5.
Claim 13
Dependent Claim
16 words
A pharmaceutical composition consisting essentially of a suitable pharmaceutical carrier and a compound of claim 6.
Claim 14
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal as effective antidepressant amount of a compound of claim 1.
Claim 15
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal an effective antidepressant amount of a compound of claim 2.
Claim 16
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal an effective antidepressant amount of a compound of claim 3.
Claim 17
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal an effective antidepressant amount of a compound of claim 4.
Claim 18
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal an effective antidepressant amount of a compound of claim 5.
Claim 19
Dependent Claim
24 words
A method of alleviating depression in a mammal which comprises administering to the mammal an effective antidepressant amount of a compound of claim 6.
References Cited (Backward Citations)
US4009273A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-30 | 1982-05-01 | 1982-10-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-30 | 1986-05-01 | 1986-10-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-30 | 1990-05-01 | 1990-10-31 | $7700.00 | Window Closed / Lapsed |