US4122170A
Expired / Lapsed
US
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Physiological vehicle compositions containing higher alkyl substituted azacyclopentan-2-ones
Assignee: Whitby Research Inc
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Filing: 1977-06-06
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Granted: 1978-10-24
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Expires: 1997-06-06
Abstract
Abstract There is disclosed an improved method for topically administering a physiologically active agent to a human or animal by dissolving an effective amount of the agent in a carrier containing suitable amounts of 1-alkyl substituted-azacyclopentan-2-one, as defined herein, and contacting the skin or other membranes of the human or animal with the resulting composition, whereby penetration of the skin or membranes is enhanced.
Inventors
- 👤 Vithal Jagannath Rajadhyaksha
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 15:33
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/06; A61K47/22; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4926; A61K9/08; A61Q; A61Q17/00; A61Q17/005; A61Q19/00; A61Q17/04; Y; Y10; Y10S; Y10S424/00; Y10S424/10
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
62 words
A method for enhancing the penetration of physiologically active agents selected from the group consisting of steroids, antibacterials and antifungals through human and animal skin and membranes comprising topically administering to a human or animal a composition comprising an effective physiological amount of said agent and an effective, penetrating amount of a compound selected from the group consisting of 1-n-octylazacyclopentan-2-one and 1-n-nonylazacyclopentan-2-one.
Claim 2
Independent Claim
62 words
A method for enhancing the penetration of physiologically active agents selected from the group consisting of steroids, antibacterials and antifungals through human and animal skin and membranes comprising topically administering to a human or animal a composition comprising an effective physiological amount of said agent and an effective, penetrating amount of a compound selected from the group consisting of 1-n-octylazacyclopentan-2-one and 1-n-nonylazacyclopentan-2-one.
Claim 3
Dependent Claim
14 words
The method of claim 1 wherein the physiologically active agent is an antibacterial agent.
Claim 4
Dependent Claim
12 words
The method of claim 2, wherein the antibacterial agent is an antibiotic.
Claim 5
Dependent Claim
23 words
The method of claim 3 wherein the antibiotic is selected from the group consisting of lincomycin, clindamycin, erythromycin and pharmaceutically useful salts thereof.
Claim 6
Dependent Claim
15 words
The method of claim 1 wherein the physiologically active agent is a physiologically active steroid.
Claim 7
Dependent Claim
14 words
The method of claim 1 wherein the physiologically active agent is an antifungal agent.
References Cited (Backward Citations)
US3085931A
Cited
US3551554A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-23 | 1982-04-24 | 1982-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-23 | 1986-04-24 | 1986-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-23 | 1990-04-24 | 1990-10-24 | $7700.00 | Window Closed / Lapsed |