US4122078A
Expired / Lapsed
US
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Antigens and antibodies of catecholamines
Assignee: Daiichi Pharmaceutical Co Ltd
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Filing: 1976-02-19
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Granted: 1978-10-24
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Expires: 1996-02-19
Abstract
Abstract An antigen consisting essentially of a catecholamine and a protein of polypeptide, wherein the protein or polypeptide is bonded to the phenyl nucleus of the catecholamine.
Inventors
- 👤 Masanori Yoshioka
- 👤 Akira Miwa
- 👤 Zenzo Tamura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 14:03
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/18; C07K16/26; Y; Y10; Y10S; Y10S436/00; Y10S436/811; Y10S436/815; Y10S436/822; Y10S530/00; Y10S530/806
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
56 words
An antigen prepared by a process, consisting essentially of: reacting a catecholamine with a protein or polypeptide carrier and an aldehyde via the Mannich reaction such that said catecholamine is attached through a substituted or unsubstituted methylene linkage to an amine group of said carrier at an unsubstituted position on the phenyl nucleus of said catecholamine.
Claim 2
Dependent Claim
56 words
An antigen prepared by a process, consisting essentially of: reacting a catecholamine with a protein or polypeptide carrier and an aldehyde via the Mannich reaction such that said catecholamine is attached through a substituted or unsubstituted methylene linkage to an amine group of said carrier at an unsubstituted position on the phenyl nucleus of said catecholamine.
Claim 3
Dependent Claim
20 words
The antigen of claim 1, wherein the catecholamine is selected from the group consisting of epinephrine, norepinephrine, dopamine and dopa.
Claim 4
Dependent Claim
12 words
The antigen of claim 1, wherein the protein is bovine serum albumin.
Claim 5
Dependent Claim
36 words
A process for producing a catecholamine specific antibody, which comprises: injecting an antigen prepared by the process of claim 1 into a host animal; withdrawing blood from said injected animal; and isolating said catecholamine specific antibodies.
Claim 6
Dependent Claim
26 words
The process of claim 4, wherein the host animal is selected from the group consisting of cows, horses, sheep, goats, pigs, guinea pigs, rats and rabbits.
Claim 7
Dependent Claim
11 words
The catecholamine specific antibody produced by a process of claim 4.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-23 | 1982-04-24 | 1982-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-23 | 1986-04-24 | 1986-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-23 | 1990-04-24 | 1990-10-24 | $7700.00 | Window Closed / Lapsed |