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US4121907A Expired / Lapsed US ⏱️ 0.0 years remaining

Sample handling system

Assignee: Coulter Electronics Inc
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Filing: 1977-06-13
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Granted: 1978-10-24
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Expires: 1997-06-13
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Abstract

Abstract A pneumatic/hydraulic sample handling system which includes a source of alternative vacuum and pressure, a normally closed, selectively operable valve to permit flow through the system withdrawing a known aliquot from a source of sample, directing said aliquot to a vessel for analysis, an isolation chamber disposed in the flow path between said source of vacuum and pressure and said vessel and having inlets respectively coupled into the flow path and a relief valve arranged between the isolation chamber and said source of vacuum and pressure, said isolation chamber having an outlet, a conduit coupling said outlet to a waste depositary, pressure differential sensitive check valve interposed in said conduit between said outlet and said waste depositary, and a microcomputer circuit arranged to control the operation of said system in accordance with a predetermined procedure.

Inventors

  • 👤 Leonard Roque

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 07:05
CPC Classifications
G; G01; G01N; G01N35/00; G01N35/10; G01N35/1095

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 167 words
A sample handling system for drawing successive aliquot volumes from a source of liquid sample, moving said aliquots singly to and through a test cell and thence to a waste depositary subsequent to the completion of the test, said system comprising: a hydraulic liquid flow system for defining a flow path, a pneumatic system operable upon said hydraulic system for moving the liquid along said flow path, an isolation chamber intermediate said hydraulic and pneumatic systems and having a pair of inlet ports respectively coupled to said hydraulic and pneumatic systems and an outlet port coupled to a waste depositary, said pneumatic system including means for generating periodic alternating pressure and vacuum, and means coupling said generating means to said isolation chamber, means coupled communicatively between said generating means and said isolation chamber for establishing an atmospheric pressure condition in said isolation chamber between each application of pressure and vacuum to said isolation chamber, and control circuit means for operating said systems according to a programmed sequence.
Claim 2
Dependent Claim 167 words
A sample handling system for drawing successive aliquot volumes from a source of liquid sample, moving said aliquots singly to and through a test cell and thence to a waste depositary subsequent to the completion of the test, said system comprising: a hydraulic liquid flow system for defining a flow path, a pneumatic system operable upon said hydraulic system for moving the liquid along said flow path, an isolation chamber intermediate said hydraulic and pneumatic systems and having a pair of inlet ports respectively coupled to said hydraulic and pneumatic systems and an outlet port coupled to a waste depositary, said pneumatic system including means for generating periodic alternating pressure and vacuum, and means coupling said generating means to said isolation chamber, means coupled communicatively between said generating means and said isolation chamber for establishing an atmospheric pressure condition in said isolation chamber between each application of pressure and vacuum to said isolation chamber, and control circuit means for operating said systems according to a programmed sequence.
Claim 3
Dependent Claim 74 words
The system as claimed in claim 1 in which said hydraulic system includes probe means immersible in the source of sample, flow cell means for receiving and holding an aliquot sample, conduit means coupled between said probe means and said flow cell means and leading therefrom to said isolation chamber, and valve means selectively operable to pass liquid along said system from said source of sample through said flow cell to said isolation chamber.
Claim 4
Dependent Claim 20 words
The system as claimed in claim 2 in which said last mentioned valve means comprise a solenoid operated pinch valve.
Claim 5
Dependent Claim 17 words
The system as claimed in claim 2 in which said generating means comprise a solenoid operated pump.
Claim 6
Dependent Claim 16 words
The system as claimed in claim 3 in which said generating means comprise a solenoid pump.
Claim 7
Dependent Claim 30 words
The system as claimed in claim 2 in which vacuum is applied to said isolation chamber and simultaneously, the valve means is operable to permit flow along said flow path.
Claim 8
Dependent Claim 26 words
The system as claimed in claim 6 in which pressure is applied to said isolation chamber to direct the content thereof to a waste delivery depositary.
Claim 9
Dependent Claim 35 words
The system as claimed in claim 7 in which said means for establishing atmospheric pressure condition in said isolation chamber comprise a relief valve coupled to said isolation chamber on the generating means side thereof.
Claim 10
Dependent Claim 48 words
The system as claimed in claim 1 in which said control circuit means comprise means for generating a plurality of pulses, means for receiving said pulses and means for correlating the number of pulses received to the operation of said pneumatic and hydraulic systems in a programmed sequence.
Claim 11
Dependent Claim 21 words
The system as claimed in claim 9 in which said means for generating a plurality of pulses comprise a variable oscillator.
Claim 12
Dependent Claim 26 words
The system as claimed in claim 9 in which said means for receiving said pulses comprise a computer, said computer having an automatic shut off mode.
Claim 13
Dependent Claim 28 words
The system as claimed in claim 11 in which said computer comprises a binary counter coupled to a read-only-memory, the outputs thereof being coupled operatively to said systems.
Claim 14
Dependent Claim 52 words
The system as claimed in claim 11 in which said computer comprises a microprocessor circuit, variable timer means and fixed timer means respectively coupled to said microprocessor circuit, read-only-memory means and random-access-memory means coupled in parallel to said microprocessor circuit and means coupling said microprocessor circuit to said systems for operating same.
Claim 15
Dependent Claim 45 words
The system as claimed in claim 2 in which said valve means comprise a normally closed solenoid operated pinch valve operable upon the flow path and said control means operates to open said pinch valve simultaneously with the application of vacuum to said isolation chamber.
Claim 16
Dependent Claim 98 words
The system as claimed in claim 1 in which said test cell comprises a flow cell, said flow cell having a body, said body having an interior chamber, said interior chamber having a pair of opposite parallel windows, inlet and outlet means, conduit means leading between said inlet and outlet means to said chamber respectively, said conduit means leading to said chamber having a U-shaped portion communicating directly to said chamber whereby liquid is swept across the window adjacent entry to said chamber, said chamber being arranged oriented to define an unobstructed optical path axially through the chamber.

References Cited (Backward Citations)

US3525592A Cited
US3557077A Cited
US3567390A Cited
US3607092A Cited
US3976429A Cited
US3948607A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-10-23 1982-04-24 1982-10-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-10-23 1986-04-24 1986-10-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-10-23 1990-04-24 1990-10-24 $7700.00 Window Closed / Lapsed

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