Patent US2399859A successfully refreshed from Google Patents.
US4118347A
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Filler for liquid chromatography
Assignee: Resonac Holdings Corp
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Filing: 1977-06-15
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Granted: 1978-10-03
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Expires: 1997-06-15
Abstract
Abstract A granular filler for liquid chromatography consisting essentially of a porous copolymer of (A) a glycidyl monovinyl ester of glycidyl monovinyl ether and (B) an alkylene glycol divinyl ester with component (A) being crosslinked by component (B) to form a gel copolymer, said copolymer containing in its molecule epoxy groups ascribable to component (A) or modified groups resulting from the ring-opening reaction of the epoxy groups with a modifying compound having a hydrophilic, oleophilic or ion exchangeable group.
Inventors
- 👤 Susumu Ishiguro
- 👤 Masuhiro Komuro
- 👤 Shigeru Nakamura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 01:49
CPC Classifications
C; C08; C08F; C08F8/00; B; B01; B01J; B01J20/00; B01J20/22; B01J20/26; B01J20/265; B01J20/267; B01J20/281; B01J20/286; C08F216/00; C08F216/12; C08F216/14; C08F216/1416; C08F220/00; C08F220/02; C08F220/10; C08F220/26; C08F220/32; C08F220/325; C08F222/00; C08F222/10; C08F222/1006; C08F222/102; C08F8/12
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
95 words
A granular filler for liquid chromatography consisting essentially of a porous copolymer of (A) a glycidyl monovinyl ester or a glycidyl monovinyl ether and (B) an alkylene glycol divinyl ester with component (A) being crosslinked by component (B) to form a gel copolymer, the mole ratio of component (A) to component (B) being 10:90 to 90:10, said copolymer containing in its molecule modified groups resulting from the ring-opening reaction of the epoxy groups ascribable to component (A) with a modifying compound selected from the group consisting of water, alkylene glycol, polyalkylene glycol and a triol.
Claim 2
Dependent Claim
95 words
A granular filler for liquid chromatography consisting essentially of a porous copolymer of (A) a glycidyl monovinyl ester or a glycidyl monovinyl ether and (B) an alkylene glycol divinyl ester with component (A) being crosslinked by component (B) to form a gel copolymer, the mole ratio of component (A) to component (B) being 10:90 to 90:10, said copolymer containing in its molecule modified groups resulting from the ring-opening reaction of the epoxy groups ascribable to component (A) with a modifying compound selected from the group consisting of water, alkylene glycol, polyalkylene glycol and a triol.
Claim 3
Dependent Claim
54 words
The filler of claim 1 wherein component (A) is a glycidyl ester of a monovinyl carboxylic acid containing 3 to 12 carbon atoms or a glycidyl ether of a monovinyl alcohol containing 3 to 12 carbon atoms, and component (B) is a mono- or poly- C 2 -C 3 alkylene glycol diacrylate or dimethacrylate.
Claim 4
Dependent Claim
19 words
The filler of claim 1 wherein the mole ratio of component (A) to component (B) is 40:60 to 80:20.
Claim 5
Dependent Claim
30 words
The filler of claim 1 wherein up to 50% of component (A) is replaced by a comonomer selected from the group consisting of methyl methacrylate, methyl acrylate and vinyl acetate.
Claim 6
Dependent Claim
21 words
The filler of claim 1 wherein the modified groups are 1,2-dihydroxyethyl groups resulting from the ring-opening hydrolysis of the epoxy groups.
Claim 7
Dependent Claim
121 words
A process for producing a granular filler for liquid chromatography, which comprises subjecting (A) 10 to 90 mole% of a glycidyl monovinyl ester or a glycidyl monovinyl ether and (B) 90 to 10 mole% of an alkylene glycol divinyl ester to aqueous suspension polymerization in the presence of an inert organic diluent being insoluble in water and capable of dissolving components (A) and (B) thereby to afford particles of a porous gel copolymer having component (A) crosslinked with component (B) and containing in its molecule epoxy groups ascribable to component (A), and reacting the resulting copolymer with a modifying compound selected from the group consisting of water, alkylene glycol, polyalkylene glycol and a triol, to modify the epoxy groups by ring-opening.
Claim 8
Dependent Claim
121 words
A process for producing a granular filler for liquid chromatography, which comprises subjecting (A) 10 to 90 mole% of a glycidyl monovinyl ester or a glycidyl monovinyl ether and (B) 90 to 10 mole% of an alkylene glycol divinyl ester to aqueous suspension polymerization in the presence of an inert organic diluent being insoluble in water and capable of dissolving components (A) and (B) thereby to afford particles of a porous gel copolymer having component (A) crosslinked with component (B) and containing in its molecule epoxy groups ascribable to component (A), and reacting the resulting copolymer with a modifying compound selected from the group consisting of water, alkylene glycol, polyalkylene glycol and a triol, to modify the epoxy groups by ring-opening.
Claim 9
Dependent Claim
54 words
The process of claim 6 wherein component (A) is a glycidyl ester of a monovinyl carboxylic acid containing 3 to 12 carbon atoms or a glycidyl ether of a monovinyl alcohol containing 3 to 12 carbon atoms, and component (B) is a mono- or poly- C 2 -C 3 alkylene glycol diacrylate or dimethacrylate.
Claim 10
Dependent Claim
19 words
The process of claim 6 wherein the mole ratio of component (A) to component (B) is 40:60 to 80:20.
Claim 11
Dependent Claim
30 words
The process of claim 6 wherein up to 50% of component (A) is replaced by a comonomer selected from the group consisitng of methyl methacrylate, methyl acrylate and vinyl acetate.
Claim 12
Dependent Claim
49 words
The process of claim 6 wherein the amount of the organic diluent is at least 30% by volume based on the total volume of components (A) and (B) and the diluent, and the amount of water is equal to, or more than, the total amount of the organic phase.
Claim 13
Dependent Claim
32 words
The process of claim 6 wherein the amount of the organic diluent is 40 to 80% by volume based on the total volume of the components (A) and (B) and the diluent.
Claim 14
Dependent Claim
20 words
The process of claim 6 wherein the modifying compound is water, and the epoxy groups are converted to 1,2-dihydroxyethyl groups.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-02 | 1982-04-03 | 1982-10-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-02 | 1986-04-03 | 1986-10-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-02 | 1990-04-03 | 1990-10-03 | $7700.00 | Window Closed / Lapsed |