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US4117112A Expired / Lapsed US ⏱️ 0.0 years remaining

Vaccine for prevention of feline leukemia

Assignee: University of Glasgow
•
Filing: 1977-05-19
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Granted: 1978-09-26
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Expires: 1997-05-19
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Abstract

Abstract The present invention encompasses a vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of an adjuvant and about 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus and having viral associated antigen on their surface wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.

Inventors

  • 👤 William Fleming Hoggan Jarrett
  • 👤 James Oswald Jarrett
  • 👤 Lindsay Joan Mackey

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 08:03
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61K; A61K40/00; A61K40/10; A61K40/40; A61K40/46; A61K2239/00; A61K2239/31; A61K2239/38; C12; C12N; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/13011; C12N2740/13022; Y; Y10; Y10S; Y10S424/00; Y10S424/819

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 57 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and about 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus and having viral associated antigen on their surface wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 2
Dependent Claim 57 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and about 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus and having viral associated antigen on their surface wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 3
Dependent Claim 60 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of aluminum hydroxide as adjuvant and about 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus and having viral associated antigen on their surface wherein the virus and cells are inactivated by chemical or physical means with destroying immunogenicity.
Claim 4
Dependent Claim 60 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of aluminum hydroxide as adjuvant and about 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus and having viral associated antigen on their surface wherein the virus and cells are inactivated by chemical or physical means with destroying immunogenicity.
Claim 5
Dependent Claim 34 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of aluminum hydroxide as adjuvant and about 1 × 10 6 FL 74 cells inactivated with paraformaldehyde.
Claim 6
Dependent Claim 34 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of aluminum hydroxide as adjuvant and about 1 × 10 6 FL 74 cells inactivated with paraformaldehyde.
Claim 7
Dependent Claim 54 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and FOCMA containing cell membrane fragments from 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 8
Dependent Claim 54 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and FOCMA containing cell membrane fragments from 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 9
Dependent Claim 21 words
A vaccine according to claim 4 wherein the cells are paraformaldehyde killed FL 74 cells and the adjuvant is aluminum hydroxide.
Claim 10
Dependent Claim 52 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and crude FOCMA extracts from 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 11
Dependent Claim 52 words
A vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of adjuvant and crude FOCMA extracts from 10 5 -10 7 feline lymphoblastoid cells chronically infected with feline leukemia virus wherein the virus and cells are inactivated by chemical or physical means without destroying immunogenicity.
Claim 12
Dependent Claim 21 words
A vaccine according to claim 6 wherein the cells are paraformaldehyde killed FL 74 cells and the adjuvant is aluminum hydroxide.

References Cited (Backward Citations)

US3966907A Cited
US4034081A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-09-25 1982-03-27 1982-09-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-09-25 1986-03-27 1986-09-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-09-25 1990-03-27 1990-09-26 $7700.00 Window Closed / Lapsed

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