US4115576A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Compositions and method of employing the same for inhibiting alcohol intoxication
Assignee: Individual
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Filing: 1976-10-26
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Granted: 1978-09-19
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Expires: 1996-10-26
Abstract
Abstract An admixture consisting essentially of two or more of the compounds selected from the group consisting of 5-hydroxymethylcytosine (5-HMC), a B 6 vitamin and nicotinamide or nicotinic acid has been found to be effective as an alcohol detoxicant and useful to inhibit alcohol intoxication. There may be added to the aforesaid admixture a calcium ion donor, such as water-soluble calcium salt selected from the group consisting of calcium chloride, calcium nitrate, calcium acetate, calcium sulfate and calcium pantothenate. Also, there may be added to the aforesaid admixture a carbohydrate, such as mannose or fructose and the compound allantoin.
Inventors
- 👤 Nathar W. Penn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 17:06
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61K31/435; A61K31/44; A61K31/445
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
60 words
A composition useful for combatting alcohol intoxication consisting essentially of 5-hydroxymethylcytosine, a B 6 vitamin selected from the group consisting of pyridoxal and derivatives or mixtures thereof, and nicotinamide or nicotinic acid, or mixtures thereof, said 5-hydroxymethylcytosine, said B 6 vitamin, and said nicotinamide or nicotinic acid being present in said composition in the molar ratio 1-6: 1-10: 1-10, respectively.
Claim 2
Dependent Claim
60 words
A composition useful for combatting alcohol intoxication consisting essentially of 5-hydroxymethylcytosine, a B 6 vitamin selected from the group consisting of pyridoxal and derivatives or mixtures thereof, and nicotinamide or nicotinic acid, or mixtures thereof, said 5-hydroxymethylcytosine, said B 6 vitamin, and said nicotinamide or nicotinic acid being present in said composition in the molar ratio 1-6: 1-10: 1-10, respectively.
Claim 3
Dependent Claim
59 words
A method of combatting alcohol intoxication in a subject which comprises administering to the subject a composition in accordance with claim 1, the components of said composition being administered to said subject in an amount in milligrams per kilogram of subject body weight in the range 10-30 5-hydroxymethylcytosine, 10-30 said B 6 vitamin, and 7-30 nicotinamide or nicotinic acid.
Claim 4
Dependent Claim
43 words
A composition useful for combatting alcohol intoxication consisting essentially of 5-hydroxymethylcytosine and a B 6 vitamin selected from the group consisting of pyridoxal and pyridoxamine, said 5-hydroxymethylcytosine and said B 6 vitamin being present in said composition in the molar ratio 1-6:1-10, respectively.
Claim 5
Dependent Claim
43 words
A composition useful for combatting alcohol intoxication consisting essentially of 5-hydroxymethylcytosine and a B 6 vitamin selected from the group consisting of pyridoxal and pyridoxamine, said 5-hydroxymethylcytosine and said B 6 vitamin being present in said composition in the molar ratio 1-6:1-10, respectively.
Claim 6
Dependent Claim
15 words
A composition in accordance with claim 3 wherein said B 6 vitamin is pyridoxal hydrochloride.
Claim 7
Dependent Claim
14 words
A composition in accordance with claim 3 wherein said B 6 vitamin is pyridoxal.
Claim 8
Dependent Claim
14 words
A composition in accordance with claim 3 wherein said B 6 vitamin is pyridoxamine.
Claim 9
Dependent Claim
15 words
A composition in accordance with claim 3 wherein said B 6 vitamin is pyridoxamine dihydrochloride.
Claim 10
Dependent Claim
54 words
A method of combatting alcohol intoxication in a subject which comprises administering to the subject a composition in accordance with claim 3, the components of said composition being administered to said subject in an amount in milligrams per kilogram of subject body weight in the range 10-30 5-hydroxymethylcytosine and 10-30 said B 6 vitamin.
Claim 11
Dependent Claim
13 words
A method in accordance with claim 8 wherein said composition is administered orally.
Claim 12
Dependent Claim
19 words
A composition in accordance with claim 8 wherein said composition is administered by injection in a physiologically acceptable carrier.
Claim 13
Dependent Claim
18 words
A composition in accordance with claim 8 wherein said composition is administered intraperitoneally in a physiologically acceptable carrier.
Claim 14
Dependent Claim
18 words
A composition in accordance with claim 8 wherein said composition is administered intravenously in a physiologically acceptable carrier.
Claim 15
Dependent Claim
13 words
A method in accordance with claim 8 wherein the subject is a human.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-09-18 | 1982-03-20 | 1982-09-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-09-18 | 1986-03-20 | 1986-09-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-09-18 | 1990-03-20 | 1990-09-19 | $7700.00 | Window Closed / Lapsed |