US4115393A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pyridyl alkyl esters of substituted phenoxy alkanoic acids having the ability to reduce the level of fatty substances in the blood
Assignee: Siegfried AG
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Filing: 1977-03-01
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Granted: 1978-09-19
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Expires: 1997-03-01
Abstract
Abstract Compounds of the formula ##STR1## WHEREIN R represents hydrogen, halogen, hydroxy or alkyl or alkoxy containing from 1 to 4 carbon atoms; X represents benzyl, benzyloxy or benzylthio, or benzyl, benzyloxy or benzylthio substituted by a said radical R; A 1 and A 2 which can be the same or different are hydrogen or alkyl radical containing up to 10 carbon atoms such that the total number of carbon atoms in A 1 and A 2 is not more than 10; n is an integer of from 1 to 3; m is 1 or 2; And pharmacologically acceptable salts thereof. These compounds have pharmaceutical utility by virtue of their ability to reduce the level of fatty substances in the blood.
Inventors
- 👤 Kurt Thiele
- 👤 Quazi Ahmed
- 👤 Rudolf Adrian
- 👤 Ulrich Jahn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 21:01
CPC Classifications
C; C07; C07C; C07C321/00; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07C59/68; C07C59/70; C07D; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/46; C07D473/00; C07D473/02; C07D473/04; C07D473/06; C07D473/08
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
85 words
A compound of the general formula ##STR16## wherein R 1 and R 2 are hydrogen, halogen, hydroxy or alkyl or alkoxy containing from 1 to 4 carbon atoms; A 1 and A 2 which can be the same or different are hydrogen or alkyl radical containing up to 10 carbon atoms such that the total number of carbon atoms in A 1 and A 2 is not more than 10; and n is an integer of from 1 to 3, and pharmacologically acceptable salts thereof.
Claim 2
Dependent Claim
85 words
A compound of the general formula ##STR16## wherein R 1 and R 2 are hydrogen, halogen, hydroxy or alkyl or alkoxy containing from 1 to 4 carbon atoms; A 1 and A 2 which can be the same or different are hydrogen or alkyl radical containing up to 10 carbon atoms such that the total number of carbon atoms in A 1 and A 2 is not more than 10; and n is an integer of from 1 to 3, and pharmacologically acceptable salts thereof.
Claim 3
Dependent Claim
43 words
A compound according to claim 1, wherein A 1 and A 2 are different alkyl groups containing from 1 to 9 carbon atoms such that the total number of carbon atoms possessed by A 1 and A 2 is not greater than 10.
Claim 4
Dependent Claim
17 words
A compound as claimed in claim 2, wherein R 1 is chlorine and R 2 is hydrogen.
Claim 5
Dependent Claim
10 words
A compound according to claim 1, wherein n is 1.
Claim 6
Dependent Claim
16 words
A compound according to claim 1 which is 2-methyl-2-[4-benzylphenoxy]valeric acid-(3-pyridyl methyl)-ester and pharmacologically acceptable salts thereof.
Claim 7
Dependent Claim
15 words
A compound according to claim 1 which is 2-methyl-2-[4-(4'-chlorobenzyl)phenoxy]valeric acid-(3-pyridylmethyl)-ester, and pharmacologically acceptable salts thereof.
Claim 8
Dependent Claim
15 words
A compound according to claim 1 which is 2-methyl-2-[4-(4'-chlorobenzyl)-phenoxy]-butyric acid-(3-oxymethylpyridine)-ester, and pharmacologically acceptable salts thereof.
Claim 9
Dependent Claim
15 words
A compound according to claim 1 which is 2-methyl-2-[4-(4'-chlorobenzyl)-phenoxy]-propionic acid-(3-pyridylmethyl)-ester, and pharmacologically acceptable salts thereof.
References Cited (Backward Citations)
US3622587A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-09-18 | 1982-03-20 | 1982-09-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-09-18 | 1986-03-20 | 1986-09-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-09-18 | 1990-03-20 | 1990-09-19 | $7700.00 | Window Closed / Lapsed |