US4110330A
Expired / Lapsed
US
⏱️ 0.0 years remaining
5'-Acetonylvincristine and related compounds
Assignee: Eli Lilly and Co
•
Filing: 1977-05-27
•
Granted: 1978-08-29
•
Expires: 1997-05-27
Abstract
Abstract 5'-Acetonylvincristine and related compounds including the corresponding 1-desmethyl derivative, useful in inhibiting the growth of experimental tumors.
Inventors
- 👤 Charles J. Barnett
- 👤 Richard A. Bimm
- 👤 George C. Cullinan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 05:01
CPC Classifications
C; C07; C07D; C07D519/00; C07D519/04
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
28 words
Compounds of the formula ##STR4## wherein Z is CO or CHOH, R 2 is H or CHO and R 1 is OH or acetoxy and pharmaceutically-acceptable salts thereof.
Claim 2
Dependent Claim
28 words
Compounds of the formula ##STR4## wherein Z is CO or CHOH, R 2 is H or CHO and R 1 is OH or acetoxy and pharmaceutically-acceptable salts thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1, said compound being 5'-acetonylvincristine.
Claim 4
Dependent Claim
10 words
A compound according to claim 1, said compound being 4-desacetyl-5'-acetonylvincristine.
Claim 5
Dependent Claim
10 words
A compound according to claim 1, said compound being 1-desformyl-4-desacetyl-5'-acetonylvincristine.
Claim 6
Dependent Claim
10 words
A sulfate salt of a compound according to claim 1.
Claim 7
Dependent Claim
10 words
A compound according to claim 1, said compound being 5'-(2"-hydroxypropyl)-4-desacetylvincristine.
Claim 8
Dependent Claim
10 words
A compound according to claim 1, said compound being 5'-(2"-hydroxypropyl)-1-desformyl-4-desacetylvincristine.
References Cited (Backward Citations)
US3097137A
Cited
US3205220A
Cited
US3370057A
Cited
US3899493A
Cited
US3887565A
Cited
US3890325A
Cited
US3954773A
Cited
US3944554A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-08-28 | 1982-02-27 | 1982-08-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-08-28 | 1986-02-27 | 1986-08-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-08-28 | 1990-02-27 | 1990-08-29 | $7700.00 | Window Closed / Lapsed |