US4108985A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dihydrocyclosporin c
Assignee: Sandoz AG
•
Filing: 1976-10-27
•
Granted: 1978-08-22
•
Expires: 1996-10-27
Abstract
Abstract The present invention provides dihydrocyclosporin C of formula, ##STR1## useful as an immunosuppressive.
Inventors
- 👤 Artur Ruegger
- 👤 Max Kuhn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 06:49
CPC Classifications
C; C12; C12N; C12N1/00; C12N1/14; C12N1/145; A; A61; A61P; A61P29/00; A61P37/00; A61P37/02; A61P37/06; C07; C07K; C07K7/00; C07K7/64; C07K7/645; A61K; A61K38/00; C12R; C12R2001/00; C12R2001/645; C12R2001/885; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/27
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
5 words
Dihydrocyclosporin C of formula ##STR4##
Claim 2
Dependent Claim
5 words
Dihydrocyclosporin C of formula ##STR4##
Claim 3
Dependent Claim
41 words
A compound of formula C 62 H 113 N 11 O 13 obtainable by hydrogenating Cyclosporin C of formula, ##STR5## which is a product of formula C 62 H 111 N 11 O 13 obtainable by cultivating the strain NRRL 8044.
Claim 4
Dependent Claim
41 words
A compound of formula C 62 H 113 N 11 O 13 obtainable by hydrogenating Cyclosporin C of formula, ##STR5## which is a product of formula C 62 H 111 N 11 O 13 obtainable by cultivating the strain NRRL 8044.
Claim 5
Dependent Claim
32 words
The compound of claim 1 of the formula C 62 H 113 N 11 O 13 having an I.R. spectrum and a N.M.R. spectrum as depicted in FIGS. 1 and 2 respectively.
Claim 6
Dependent Claim
8 words
A compound of claim 1 in amorphous form.
Claim 7
Dependent Claim
22 words
A pharmaceutical composition comprising a therapeutically effective amount of a compound of claim 1 in association with a pharmaceutical carrier or diluent.
Claim 8
Dependent Claim
29 words
A method of stimulating humoral immunity in animals which comprises administering a therapeutically effective amount of a compound of claim 1 to an animal in need of such treatment.
Claim 9
Dependent Claim
32 words
A method of stimulating immunosuppressive activity in cellular immunity in animals which comprises administering a therapeutically effective amount of a compound of claim 1 to an animal in need of such treatment.
Claim 10
Dependent Claim
29 words
A method of treating chronic inflammations in animals which comprises administering a therapeutically effective amount of a compound of claim 1 to an animal in need of such treatment.
Claim 11
Dependent Claim
28 words
A method of treating polyarthritis in animals which comprises administering a therapeutically effective amount of a compound of claim 1 to an animal in need of such treatment.
References Cited (Backward Citations)
DE2455859A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-08-21 | 1982-02-20 | 1982-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-08-21 | 1986-02-20 | 1986-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-08-21 | 1990-02-20 | 1990-08-22 | $7700.00 | Window Closed / Lapsed |