US4107328A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antimicrobial compositions and methods for utilizing the same employing mixtures of amines
Assignee: Biosyn Inc
•
Filing: 1977-05-26
•
Granted: 1978-08-15
•
Expires: 1997-05-26
Abstract
Abstract There are provided antimicrobial compositions of the low toxicity having enhanced activity against gram positive and gram negative bacteria as well as fungi or protozoa and consists essentially of:
Inventors
- 👤 Edwin B. Michaels
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 11:47
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A01; A01N; A01N33/00; A01N33/16; A01N33/24; A01N37/00; A01N37/18; A01N37/20; A01N37/44; A01N37/46; A01N41/00; A01N41/02; A01N41/04; A61K31/00; A61K31/185; A61K31/205; A61K8/44; A61Q; A61Q15/00; A61Q17/00; A61Q17/005; A61Q19/00; A61Q19/10; A61Q5/00; A61Q5/02; C; C11; C11D; C11D1/00; C11D1/66; C11D1/75; C11D1/88; C11D1/94; C11D3/00; C11D3/0005; C11D3/0068; C11D3/48
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
112 words
A broad spectrum, antimicrobial composition having low toxicity which consists of: (a) from 0.1 to 40 parts, by weight, of a higher alkyl-N-betaine, said betaine having the structure: ##STR3## where R is a higher alkyl of from 10 to 18 carbon atoms, or mixed alkyl of the same, (b) from 0.1 to 40 parts, by weight, of a higher alkyl-N,N-dimethylamine oxide, a higher alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl of from 10 to 18 carbon atoms, or mixed alkyl of the same, and (c) a protonating agent, sufficient to adjust the pH of said composition from 4.0 to 5.5.
Claim 2
Dependent Claim
112 words
A broad spectrum, antimicrobial composition having low toxicity which consists of: (a) from 0.1 to 40 parts, by weight, of a higher alkyl-N-betaine, said betaine having the structure: ##STR3## where R is a higher alkyl of from 10 to 18 carbon atoms, or mixed alkyl of the same, (b) from 0.1 to 40 parts, by weight, of a higher alkyl-N,N-dimethylamine oxide, a higher alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide having the respective structure: ##STR4## where R 1 is a higher alkyl of from 10 to 18 carbon atoms, or mixed alkyl of the same, and (c) a protonating agent, sufficient to adjust the pH of said composition from 4.0 to 5.5.
Claim 3
Dependent Claim
21 words
The composition of claim 1, wherein from 1 to 20 parts of each of said betaine and amine oxide are present.
Claim 4
Dependent Claim
11 words
The composition according to claim 1, wherein the alkyl-N-betaine is coco-N-betaine.
Claim 5
Dependent Claim
11 words
The composition according to claim 1, wherein the alkyl-N-betaine is stearyl-N-betaine.
Claim 6
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is stearyl-N,N-dimethylamine oxide.
Claim 7
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is myristyl/palmitic-N,N-dimethylamine oxide.
Claim 8
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is coco-N,N-dimethylamine oxide.
Claim 9
Dependent Claim
14 words
The composition according to claim 1, wherein the higher alkylamine oxide is stearyl-N,N-dihydroxyethylamine oxide.
Claim 10
Dependent Claim
13 words
The composition according to claim 1, wherein the protonating agent is citric acid.
Claim 11
Dependent Claim
13 words
The composition according to claim 1, wherein the protonating agent is acetic acid.
Claim 12
Dependent Claim
31 words
The composition according to claim 1, wherein the said composition is in an aqueous medium and the pH thereof is adjusted to and maintained at from about 4.7 to about 5.2.
Claim 13
Dependent Claim
32 words
A method for inhibiting the growth of microorganisms selected from the class consisting of bacteria, fungi and protozoa which comprises: applying thereto an antimicrobially effective amount of the composition of claim 1.
Claim 14
Dependent Claim
11 words
The method according to claim 12, wherein the microorganisms are bacteria.
Claim 15
Dependent Claim
16 words
The method according to claim 12, wherein the growth of microorganisms are inhibited in incised wounds.
Claim 16
Dependent Claim
16 words
The method according to claim 12, wherein the growth of microorganisms are inhibited in pyogenic wounds.
Claim 17
Dependent Claim
25 words
The method according to claim 12, wherein the antimicrobially effective amount is defined as containing from 1 to 20 parts, by weight, of said composition.
References Cited (Backward Citations)
US3484523A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-08-14 | 1982-02-13 | 1982-08-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-08-14 | 1986-02-13 | 1986-08-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-08-14 | 1990-02-13 | 1990-08-15 | $7700.00 | Window Closed / Lapsed |