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US4097588A Expired / Lapsed US ⏱️ 0.0 years remaining

Mineralizing dental mouthrinse

Assignee: National Research Development Corp UK
•
Filing: 1976-03-08
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Granted: 1978-06-27
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Expires: 1996-03-08
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Abstract

Abstract A dental mouthrinse is provided which is in the form of a clear solution saturated with respect to brushite and preferably also containing a source of fluoride ions such as to provide for example 3 to 20 ppm fluoride ions and a buffer with a molarity of for example 0.15 to 0.3M to provide a pH of 5.8 to 7.0. The mouth rinse is prepared by adding solid brushite to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C, the solution is separated from excess brushite to provide a clear solution and the clear solution is allowed to come to an ambient temperature greater than 15° C. Further ingredients of the mouth rinse may be added together with the solid brushite or to the clear solution after it has been allowed to come to ambient temperature. The mouth rinse is capable of recalcifying both dentine and tooth enamel and is particularly suitable for recalcifying early decayed areas in teeth.

Inventors

  • 👤 Ronnie Stuart Levine

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 15:32
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/24; A61K8/20; A61K8/21; A61Q; A61Q11/00

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 74 words
A mouthrinse composition saturated with respect to brushite, said composition being in the form of a clear solution and wherein said composition has been prepared by adding solid brushite to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C., separating said solution from excess brushite to provide a clear solution, and allowing said clear solution to come to an ambient temperature greater than 15° C.
Claim 2
Dependent Claim 74 words
A mouthrinse composition saturated with respect to brushite, said composition being in the form of a clear solution and wherein said composition has been prepared by adding solid brushite to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C., separating said solution from excess brushite to provide a clear solution, and allowing said clear solution to come to an ambient temperature greater than 15° C.
Claim 3
Dependent Claim 14 words
A composition according to claim 1 containing in addition a source of fluoride ions.
Claim 4
Dependent Claim 13 words
A composition according to claim 2 containing 3 to 20 ppm fluoride ions.
Claim 5
Dependent Claim 11 words
A composition according to claim 2 containing in addition a buffer.
Claim 6
Dependent Claim 19 words
A composition according to claim 4 in which said buffer has a molarity in the range 0.15 to 0.3M.
Claim 7
Dependent Claim 17 words
A composition according to claim 5 in which said buffe is potassium dihydrogen orthophosphate/disodium hydrogen orthophosphate dihydrate.
Claim 8
Dependent Claim 13 words
A composition according to claim 4 having a pH of 5.8 to 7.0.
Claim 9
Dependent Claim 27 words
A composition according to claim 1 containing at least one additional mouth rinse component selected from the group consisting of preserving agents, flavouring agents and antiseptic agents.
Claim 10
Independent Claim 92 words
A method of making a mouth rinse in which solid brushite, a source of flouride ions and a buffer are added to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C having a fluoride ion concentration of 3 to 20 ppm, a buffer molarity of 0.15 to 0.3M and a pH of 5.8 to 7.0 said solution is separated from excess brushite to provide a clear solution and said clear solution is allowed to come to an ambient temperature greater than 15° C.
Claim 11
Independent Claim 92 words
A method of making a mouth rinse in which solid brushite, a source of flouride ions and a buffer are added to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C having a fluoride ion concentration of 3 to 20 ppm, a buffer molarity of 0.15 to 0.3M and a pH of 5.8 to 7.0 said solution is separated from excess brushite to provide a clear solution and said clear solution is allowed to come to an ambient temperature greater than 15° C.
Claim 12
Independent Claim 60 words
A method of making a mouth rinse in which solid brushite is added to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C, said solution is separated from excess brushite to provide a clear solution and said clear solution is allowed to come to an ambient temperature greater than 15° C.
Claim 13
Independent Claim 60 words
A method of making a mouth rinse in which solid brushite is added to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C, said solution is separated from excess brushite to provide a clear solution and said clear solution is allowed to come to an ambient temperature greater than 15° C.
Claim 14
Dependent Claim 24 words
A method according to claim 10 in which further ingredients of said mouth rinse are added to said water together with said solid brushite.
Claim 15
Dependent Claim 30 words
A method according to claim 10 in which further ingredients of said mouth rinse are added to said clear solution after it has been allowed to come to ambient temperature.
Claim 16
Dependent Claim 19 words
A method according to claim 10 in which said mouth rinse contans in addition a source of fluoride ions.
Claim 17
Dependent Claim 18 words
A method according to claim 13 in which said mouth rinse contains 3 to 20 ppm fluoride ions.
Claim 18
Dependent Claim 16 words
A method according to claim 13 in which said mouth rinse contains in addition a buffer.
Claim 19
Dependent Claim 19 words
A method according to claim 15 in which said buffer has a molarity in the range 0.15 to 0.3M.
Claim 20
Dependent Claim 17 words
A method according to claim 16 in which said buffer is potassium dihydrogen orthophosphate/disodium hydrogen orthophosphate dihydrate.
Claim 21
Dependent Claim 20 words
A method according to claim 15 in which said mouth rinse is produced with a pH of 5.8 to 7.0.
Claim 22
Dependent Claim 34 words
A method according to claim 15 in which said mouth rinse is produced containing at least one additional mouth rinse component selected from the group consisting of preserving agents, flavouring agents and antiseptic agents.
Claim 23
Dependent Claim 23 words
A method of treating or reducing the incidence of dental caries in humans which comprises administering a mouthrinse composition according to claim 1.
Claim 24
Independent Claim 116 words
A method of treating or reducing the incidence of dental caries in humans which comprises administering a mouthrinse composition in the form of a clear solution saturated with respect to brushite, said solution having a pH of 5.8 to 7.0, containing 3 to 20 ppm fluoride ions and a buffer having a molarity in the range of 0.15 to 0.3M and wherein said composition has been prepared by adding solid brushite to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C., separating said solution from excess brushite to provide a clear solution, and allowing said clear solution to come to an ambient temperature greater than 15° C.
Claim 25
Independent Claim 116 words
A method of treating or reducing the incidence of dental caries in humans which comprises administering a mouthrinse composition in the form of a clear solution saturated with respect to brushite, said solution having a pH of 5.8 to 7.0, containing 3 to 20 ppm fluoride ions and a buffer having a molarity in the range of 0.15 to 0.3M and wherein said composition has been prepared by adding solid brushite to water to provide a solution containing excess solid brushite at a temperature of from 0° to 15° C., separating said solution from excess brushite to provide a clear solution, and allowing said clear solution to come to an ambient temperature greater than 15° C.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-06-26 1981-12-26 1982-06-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-06-26 1985-12-26 1986-06-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-06-26 1989-12-26 1990-06-27 $7700.00 Window Closed / Lapsed

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