US4096262A
Expired / Lapsed
US
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Pour-on anthelmintics
Assignee: Bayer AG
•
Filing: 1977-03-03
•
Granted: 1978-06-20
•
Expires: 1997-03-03
Abstract
Abstract An anthelmintic composition suitable for pour-on application to animals for the treatment of helmintic infections which comprises from 0.5 to 40 parts by weight of an anthelmintic agent which is capable of penetrating the skin of the animal to be treated, 0.5 to 50 parts by weight of one or more spreading oils, 20 to 95 parts by weight of one or more suitable organic or inorganic solvents and 0 to 20 parts by weight of one or more auxiliaries.
Inventors
- 👤 Peter Andrews
- 👤 Hubert Dorn
- 👤 Manfred Federmann
- 👤 Herbert Voege
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 10:51
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K9/0017; A61P; A61P17/00
Claims Analysis
Total Claims: 38
Claim 1
Independent Claim
125 words
An anthelmintic composition suitable for pour-on application to animals for the treatment of helminthic infections which comprises 5 to 20 percent by weight of an anthelmintic agent which is capable of penetrating the skin of the animal to be treated, 1 to 30 percent by weight of one or more spreading oils, selected from the group consisting of isopropyl myristate isopropyl palmitate, caprylic/caproic acid triglyceride, saturated triglycerides of natural fatty acids and waxy fatty acid esters which correspond to synthetic duck uropygial gland fat and 60 to 90 percent by weight of one or more solvents selected from the group consisting of isopropanol, amyl alcohol, methyl ethyl ketone, glycol ethers and methylene chloride, and 0 to 10 percent by weight of one or more auxiliaries.
Claim 2
Dependent Claim
125 words
An anthelmintic composition suitable for pour-on application to animals for the treatment of helminthic infections which comprises 5 to 20 percent by weight of an anthelmintic agent which is capable of penetrating the skin of the animal to be treated, 1 to 30 percent by weight of one or more spreading oils, selected from the group consisting of isopropyl myristate isopropyl palmitate, caprylic/caproic acid triglyceride, saturated triglycerides of natural fatty acids and waxy fatty acid esters which correspond to synthetic duck uropygial gland fat and 60 to 90 percent by weight of one or more solvents selected from the group consisting of isopropanol, amyl alcohol, methyl ethyl ketone, glycol ethers and methylene chloride, and 0 to 10 percent by weight of one or more auxiliaries.
Claim 3
Dependent Claim
19 words
A composition according to claim 1 wherein the anthelmintic agent is a compound of the benzimidazole or isoquinoline series.
Claim 4
Dependent Claim
12 words
A composition according to claim 1 wherein the anthelmintic agent is tetramisole.
Claim 5
Dependent Claim
12 words
A composition according to claim 1 wherein the anthelmintic agent is levamisole.
Claim 6
Dependent Claim
12 words
A composition according to claim 1 wherein the anthelmintic agent is 2-(cyclohexanecarbonyl)-4-oxo-1,2,3,6,7,11-b-hexahydro-4H-pyrazino-(2,1-a)-isoquinoline.
Claim 7
Dependent Claim
12 words
A composition according to claim 1 wherein the anthelmintic agent is 5,5'-dichloro-3,3'-dinitrobiphenyl-2,2'-diol.
Claim 8
Dependent Claim
32 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 9
Dependent Claim
33 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in a weight ratio of 10:1 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 10
Dependent Claim
33 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in a weight ratio of 2:1 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 11
Dependent Claim
33 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in a weight ratio of 1:3 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 12
Dependent Claim
33 words
A composition according to claim 1 which comprises levamisole base and isopropyl palmitate in a weight ratio of 10:3 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 13
Dependent Claim
33 words
A composition according to claim 1 which comprises levamisole base and caprylic/caproic acid triglyceride in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 14
Dependent Claim
35 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in a weight ratio of 1:3.6 and methyl ethyl ketone in an amount sufficient to make up a 100 ml. unit dosage.
Claim 15
Dependent Claim
37 words
A composition according to claim 1 which comprises levamisole base, methylene chloride and polyoxyethylated castor oil in a weight ratio of 1:2:0.75 and isopropyl myristate in an amount sufficient to make up a 100 ml. unit dosage.
Claim 16
Dependent Claim
32 words
A composition according to claim 1 which comprises levamisole base and Softisan® in a weight ratio of 1:2 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 17
Dependent Claim
43 words
A composition according to claim 1 which comprises levamisole base and waxy branched fatty acid esters which correspond to synthetic duck uropygial gland fat in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 18
Dependent Claim
36 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in a weight ratio of 2:1 and dipropylene glycol monomethyl ether in an amount sufficient to make up a 100 ml. unit dosage.
Claim 19
Dependent Claim
35 words
A composition according to claim 1 which comprises levamisole base and isopropyl myristate in equal proportions by weight and dipropylene glycol monomethyl ether in an amount sufficient to make up a 100 ml. unit dosage.
Claim 20
Independent Claim
137 words
A method of treating helminthic infections in animals which comprises pouring onto the skin of the animal to be treated an anthelmintically effective amount of a composition which comprises 5 to 20 percent by weight of an anthelmintic agent which is capable of penetrating the skin of the animal to be treated, 1 to 30 percent by weight of one or more spreading oils, selected from the group consisting of isopropyl myristate isopropyl palmitate, caprylic/caproic acid triglyceride, saturated triglycerides of natural fatty acids and waxy fatty acid esters which correspond to synthetic duck uropygial gland fat and 60 to 90 percent by weight of one or more solvents selected from the group consisting of isopropanol, amyl alcohol, methyl ethyl ketone, glycol ethers and methylene chloride, and 0 to 10 percent by weight of one or more auxiliaries.
Claim 21
Independent Claim
137 words
A method of treating helminthic infections in animals which comprises pouring onto the skin of the animal to be treated an anthelmintically effective amount of a composition which comprises 5 to 20 percent by weight of an anthelmintic agent which is capable of penetrating the skin of the animal to be treated, 1 to 30 percent by weight of one or more spreading oils, selected from the group consisting of isopropyl myristate isopropyl palmitate, caprylic/caproic acid triglyceride, saturated triglycerides of natural fatty acids and waxy fatty acid esters which correspond to synthetic duck uropygial gland fat and 60 to 90 percent by weight of one or more solvents selected from the group consisting of isopropanol, amyl alcohol, methyl ethyl ketone, glycol ethers and methylene chloride, and 0 to 10 percent by weight of one or more auxiliaries.
Claim 22
Dependent Claim
19 words
A method according to claim 19 wherein the anthelmintic agent is a compound of the benzimidazole or isoquinoline series.
Claim 23
Dependent Claim
12 words
A method according to claim 19 wherein the anthelmintic agent is tetramisole.
Claim 24
Dependent Claim
12 words
A method according to claim 19 wherein the anthelmintic agent is levamisole.
Claim 25
Dependent Claim
12 words
A method according to claim 19 wherein the anthelmintic agent is 2-(cyclohexanecarbonyl)-4-oxo-1,2,3,6,7,11-b-hexahydro-4H-pyrazino-(2,1-a)-isoquinoline.
Claim 26
Dependent Claim
12 words
A method according to claim 19 wherein the anthelmintic agent is 5,5'-dichloro-3,3'-dinitrobiphenyl-2,2'-diol.
Claim 27
Dependent Claim
34 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 28
Dependent Claim
35 words
A method according to claim 19 wherein the composition comprises levamisol base and isopropyl myristate in a weight ratio of 10:1 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 29
Dependent Claim
35 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in a weight ratio of 2:1 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 30
Dependent Claim
35 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in a weight ratio of 1:3 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 31
Dependent Claim
35 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl palmitate in a weight ratio of 10:3 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 32
Dependent Claim
35 words
A method according to claim 19 wherein the composition comprises levamisole base and caprylic/caproic acid triglyceride in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 33
Dependent Claim
37 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in a weight ratio of 1:3.6 and methyl ethyl ketone in an amount sufficient to make up a 100 ml. unit dosage.
Claim 34
Dependent Claim
39 words
A method according to claim 19 wherein the composition comprises levamisole base, methylene chloride and polyoxyethylated castor oil in a weight ratio of 1:2:0.75 and isopropyl myristate in an amount sufficient to make up a 100 ml. unit dosage.
Claim 35
Dependent Claim
34 words
A method according to claim 19 wherein the composition comprises levamisole base and Softisan® in a weight ratio of 1:2 and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 36
Dependent Claim
45 words
A method according to claim 19 wherein the composition comprises levamisole base and waxy branched fatty acid esters which correspond to synthetic duck uropygial gland fat in equal proportions by weight and isopropanol in an amount sufficient to make up a 100 ml. unit dosage.
Claim 37
Dependent Claim
38 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in a weight ratio of 2:1 and dipropylene glycole monomethyl ether in an amount sufficient to make up a 100 ml. unit dosage.
Claim 38
Dependent Claim
37 words
A method according to claim 19 wherein the composition comprises levamisole base and isopropyl myristate in equal proportions by weight and dipropylene glycol monomethyl ether in an amount sufficient to make up a 100 ml. unit dosage.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-19 | 1981-12-19 | 1982-06-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-19 | 1985-12-19 | 1986-06-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-19 | 1989-12-19 | 1990-06-20 | $7700.00 | Window Closed / Lapsed |