US4096247A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Gold thio glucopyranoside compounds and method of use
Assignee: GlaxoSmithKline LLC
•
Filing: 1977-02-16
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Granted: 1978-06-20
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Expires: 1997-02-16
Abstract
Abstract A new series of lower alkyl ethers of S-tri-lower-alkylphosphinegold 1-thio-β-D-glucopyranoside has been prepared and found to have anti-arthritic activity and, in particular, are of use in the treatment of rheumatoid arthritis.
Inventors
- 👤 Ivan Lantos
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 05:21
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/02; C07H15/04; A; A61; A61P; A61P29/00; C07H23/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
21 words
A chemical compound of the formula: ##STR2## in which: R and R 1 are each respectively lower alkyl of 1-4 carbons.
Claim 2
Dependent Claim
21 words
A chemical compound of the formula: ##STR2## in which: R and R 1 are each respectively lower alkyl of 1-4 carbons.
Claim 3
Dependent Claim
10 words
A compound of claim 1 in which R is methyl.
Claim 4
Dependent Claim
15 words
A compound of claim 1 in which R is methyl and R 1 is ethyl.
Claim 5
Dependent Claim
24 words
A pharmaceutical composition having anti-arthritic activity, in dosage unit form, comprising a pharmaceutical carrier and an effective amount of a compound of claim 1.
Claim 6
Dependent Claim
26 words
A method of producing anti-arthritic activity which comprises administering internally to a subject in need of treatment an effective amount of a compound of claim 1.
Claim 7
Dependent Claim
16 words
The method of claim 5 in which the compound is S-triethylphosphinegold(I) 2,3,4,6-tetra-O-methyl-1-thio-β-D-glucopyranoside which is administered orally.
Claim 8
Dependent Claim
22 words
The method of claim 6 in which the daily dosage is chosen from the range of from 1-12 mg of active ingredient.
References Cited (Backward Citations)
US3635945A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-19 | 1981-12-19 | 1982-06-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-19 | 1985-12-19 | 1986-06-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-19 | 1989-12-19 | 1990-06-20 | $7700.00 | Window Closed / Lapsed |