US4096173A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Chlorinated 1-aminoindane N-methyl transferase inhibitors
Assignee: Eli Lilly and Co
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Filing: 1977-03-28
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Granted: 1978-06-20
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Expires: 1997-03-28
Abstract
Abstract 4-Chloro and 4,5-, 5,6- and 6,7-dichloro-1-aminoindanes, useful as inhibitors of norephineprine N-methyl transferase.
Inventors
- 👤 Bryan B. Molloy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 15:29
CPC Classifications
C; C07; C07C; C07C51/00; C07C51/347; C07C51/353
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
19 words
A compound selected from the group consisting of 4-chloro-1-aminoindane, 4,5-dichloro-1-aminoindane, 5,6-dichloro-1-aminoindane and 6,7-dichloro-1-aminoindane and pharmaceutically-acceptable acid addition salts thereof.
Claim 2
Dependent Claim
19 words
A compound selected from the group consisting of 4-chloro-1-aminoindane, 4,5-dichloro-1-aminoindane, 5,6-dichloro-1-aminoindane and 6,7-dichloro-1-aminoindane and pharmaceutically-acceptable acid addition salts thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1, said compound being 4-chloro-1-aminoindane.
Claim 4
Dependent Claim
10 words
A compound according to claim 1, said compound being 4,5-dichloro-1-aminoindane.
Claim 5
Dependent Claim
10 words
A compound according to claim 1, said compound being 5,6-dichloro-1-aminoindane.
Claim 6
Dependent Claim
10 words
A compound according to claim 1, said compound being 6,7-dichloro-1-aminoindane.
Claim 7
Dependent Claim
9 words
The hydrochloride salt of the compound of claim 2.
Claim 8
Dependent Claim
9 words
The maleate salt of the compound of claim 3.
Claim 9
Dependent Claim
32 words
A compound of the formula ##STR3## wherein two of R 1 , R 2 , R 3 and R 4 are vicinal chlorine atoms and two are hydrogen; and pharmaceutically-acceptable salts thereof.
Claim 10
Dependent Claim
32 words
A compound of the formula ##STR3## wherein two of R 1 , R 2 , R 3 and R 4 are vicinal chlorine atoms and two are hydrogen; and pharmaceutically-acceptable salts thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-19 | 1981-12-19 | 1982-06-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-19 | 1985-12-19 | 1986-06-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-19 | 1989-12-19 | 1990-06-20 | $7700.00 | Window Closed / Lapsed |