US4093711A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral hygiene
Assignee: Noxell Corp
•
Filing: 1976-08-13
•
Granted: 1978-06-06
•
Expires: 1996-08-13
Abstract
Abstract Method for retarding pellicle and plaque formation which includes contacting sites of plaque formation and growth with dental preparation containing certain amine oxide compounds and dental preparations containing the amine oxide compounds.
Inventors
- 👤 Owen Rodney Blackburne
- 👤 Warren B. Shapiro
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 01:53
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
163 words
A method for retarding pellicle and plaque formation which comprises intermittently contacting sites of plaque formation and growth with a preparation comprising an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR17## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms, n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; and each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; and wherein said heterocyclic ring is selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl.
Claim 2
Independent Claim
163 words
A method for retarding pellicle and plaque formation which comprises intermittently contacting sites of plaque formation and growth with a preparation comprising an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR17## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms, n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; and each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; and wherein said heterocyclic ring is selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl.
Claim 3
Dependent Claim
12 words
The method of claim 1 wherein R is a monovalent hydrocarbyl group.
Claim 4
Dependent Claim
12 words
The method of claim 1 wherein R is an aliphatic hydrocarbon group.
Claim 5
Dependent Claim
15 words
The method of claim 1 wherein R contains from 13 to about 21 carbon atoms.
Claim 6
Dependent Claim
15 words
The method of claim 1 wherein R contains from 15 to about 21 carbon atoms.
Claim 7
Dependent Claim
15 words
The method of claim 1 wherein R contains from 15 to about 17 carbon atoms.
Claim 8
Dependent Claim
12 words
The method of claim 1 wherein R 1 is hydrogen or methyl
Claim 9
Dependent Claim
10 words
The method of claim 1 wherein R 1 is H.
Claim 10
Dependent Claim
13 words
The method of claim 1 wherein A is an alkylene or alkylidene group.
Claim 11
Dependent Claim
19 words
The method of claim 1 wherein A is an alkylene or alkylidene group containing 1 to 3 carbon atoms.
Claim 12
Dependent Claim
22 words
The method of claim 1 wherein each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms.
Claim 13
Dependent Claim
19 words
The method of claim 1 wherein each R 2 individually is an alkyl group containing from 1-3 carbon atoms.
Claim 14
Dependent Claim
10 words
The method of claim 1 wherein R 2 is methyl.
Claim 15
Dependent Claim
10 words
The method of claim 1 wherein R 2 is ethyl.
Claim 16
Dependent Claim
34 words
The method of claim 1 wherein R 1 is H, A is an alkylene or alkylidene group containing from 1 to 3 carbon atoms and each R 2 group individually is methyl or ethyl.
Claim 17
Dependent Claim
12 words
The method of claim 1 wherein R is an aliphatic hydrocarbon group.
Claim 18
Dependent Claim
13 words
The method of claim 1 wherein said compound is dimethylaminopropyl tallow amide N-oxide.
Claim 19
Dependent Claim
17 words
The method of claim 1 wherein said compound is diethylaminopropylpalmitamide N-oxide or dimethylaminopropylpalmitamide N-oxide or mixtures thereof.
Claim 20
Dependent Claim
11 words
The method of claim 1 wherein said compound is dimethylaminopropyloleamide N-oxide.
Claim 21
Dependent Claim
12 words
The method of claim 1 wherein said compound is dimethylaminopropyl stearamide N-oxide.
Claim 22
Dependent Claim
12 words
The method of claim 1 wherein said compound is dimethylaminopropyl myristamide N-oxide.
Claim 23
Dependent Claim
11 words
The method of claim 1 wherein said compound is dimethylaminopropylpentadecanamide N-oxide.
Claim 24
Dependent Claim
12 words
The method of claim 1 which comprises intermittently contacting the oral cavity.
Claim 25
Dependent Claim
18 words
The method of claim 1 wherein the preparation contains at least about 0.1% by weight of the compound.
Claim 26
Dependent Claim
20 words
The method of claim 1 wherein the preparation contains from about 1 to about 25% by weight of the compound.
Claim 27
Dependent Claim
50 words
The method of claim 1 wherein said preparation also contains from about 5 to about 60% by weight of an abrasive polishing agent; from about 0.5 to about 5% by weight of a sudsing agent; from about 0.1 to about 15% by weight of a thickening agent; water and humectants.
Claim 28
Dependent Claim
30 words
The method of claim 1 wherein said preparation is in the form of a mouthwash and further includes a sudsing agent, ethyl alcohol, a humectant, sweetener, flavoring agent, and water.
Claim 29
Dependent Claim
20 words
The method of claim 1 wherein said preparation is in the form of a prophylactic paste which further includes pumice.
Claim 30
Dependent Claim
10 words
The method of claim 1 wherein said preparation contains water.
Claim 31
Dependent Claim
185 words
A dental preparation retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR18## wherein R is a monovalent or divalent hydrocarbon group containing at least 13 carbon atoms, n is one when R is monovalent and is 2 when R is divalent, R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms, A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms, each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms, or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring, and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; from about 5 to about 50% by weight of an abrasive polishing agent; from about 0.5 to about 5% by weight of a sudsing agent; from about 0.1 to about 15% by weight of a thickening agent; and water.
Claim 32
Dependent Claim
185 words
A dental preparation retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR18## wherein R is a monovalent or divalent hydrocarbon group containing at least 13 carbon atoms, n is one when R is monovalent and is 2 when R is divalent, R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms, A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms, each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms, or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring, and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; from about 5 to about 50% by weight of an abrasive polishing agent; from about 0.5 to about 5% by weight of a sudsing agent; from about 0.1 to about 15% by weight of a thickening agent; and water.
Claim 33
Dependent Claim
152 words
A dental preparation in the form of a mouthwash for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR19## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; a sudsing agent; ethyl alcohol; a humectant; sweetner; flavoring agent; and water.
Claim 34
Dependent Claim
152 words
A dental preparation in the form of a mouthwash for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR19## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; a sudsing agent; ethyl alcohol; a humectant; sweetner; flavoring agent; and water.
Claim 35
Dependent Claim
156 words
A dental preparation in the form of a prophylactic paste for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR20## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring, and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; and pumice.
Claim 36
Dependent Claim
156 words
A dental preparation in the form of a prophylactic paste for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR20## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring, and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; and pumice.
Claim 37
Dependent Claim
151 words
A dental preparation for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR21## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; water; and ethyl alcohol.
Claim 38
Dependent Claim
151 words
A dental preparation for retarding pellicle and plaque formation which comprises an amount sufficient to retard pellicle and plaque formation of at least one compound of the formula: ##STR21## wherein R is a monovalent or divalent hydrocarbyl group containing at least 13 carbon atoms; n is one when R is monovalent and is 2 when R is divalent; R 1 is H or an alkyl group containing from 1 to about 3 carbon atoms; A is a divalent hydrocarbon bridge containing from 1 to about 6 carbon atoms; each R 2 individually is an alkyl group containing from 1 to about 5 carbon atoms; or both R 2 groups are interconnected to form a heterocyclic ring with the N atom to which they are attached and contain 5 to 6 members in the ring; and being selected from the group consisting of morpholinyl, piperidinyl, pyrrolidinyl, and piperazinyl; water; and ethyl alcohol.
Claim 39
Dependent Claim
11 words
The method of claim 1 wherein said preparation includes hydrated alumina.
Claim 40
Dependent Claim
11 words
The method of claim 1 wherein said preparation includes polyoxyalkylene polyol.
References Cited (Backward Citations)
US3206512A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-06-05 | 1981-12-05 | 1982-06-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-06-05 | 1985-12-05 | 1986-06-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-06-05 | 1989-12-05 | 1990-06-06 | $7700.00 | Window Closed / Lapsed |