US4086924A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Plasmapheresis apparatus
Assignee: Haemonetics Corp
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Filing: 1976-10-06
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Granted: 1978-05-02
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Expires: 1996-10-06
Abstract
Abstract Plasmapheresis apparatus is disclosed which comprises a unique combination of blood withdrawal, separation and return means, together with automatic cycle control means. This apparatus can withdraw whole blood from a donor, separate it into plasma and non-plasma components, and return the non-plasma component to the donor while the donor remains connected to the apparatus throughout the entire procedure. Standard quantities of separated plasma can be obtained in significantly reduced times, and the possibility of mistakenly returning wrong blood components to the donor is eliminated.
Inventors
- 👤 Allen Latham, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 22:12
CPC Classifications
B; B04; B04B; B04B5/00; B04B5/04; B04B5/0442; A; A61; A61M; A61M1/00; A61M1/14; A61M1/30; A61M1/301; A61M1/304; A61M1/36; A61M1/3693; A61M1/3696; B04B2005/0464
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
143 words
Plasmapheresis apparatus, comprising, in combination: means for withdrawing whole blood from a donor; means for supplying anticoagulant to said withdrawn whole blood; means for separating anticoagulated whole blood into plasma and non-plasma components; means for transporting anticoagulated, withdrawn, whole blood to said means for separating; a plasma container for receiving plasma from said means for separating; means for detecting when a predetermined quantity of separated plasma component has been introduced into said plasma container; means for returning non-plasma components from said means for separating to said donor; means for monitoring when said non-plasma components have been returned to said donor; and, cycle control means for immediately switching from a withdraw cycle to a return cycle in response to said means for detecting and for immediately switching from a return cycle to a withdraw or stand-by cycle in response to said means for monitoring.
Claim 2
Dependent Claim
143 words
Plasmapheresis apparatus, comprising, in combination: means for withdrawing whole blood from a donor; means for supplying anticoagulant to said withdrawn whole blood; means for separating anticoagulated whole blood into plasma and non-plasma components; means for transporting anticoagulated, withdrawn, whole blood to said means for separating; a plasma container for receiving plasma from said means for separating; means for detecting when a predetermined quantity of separated plasma component has been introduced into said plasma container; means for returning non-plasma components from said means for separating to said donor; means for monitoring when said non-plasma components have been returned to said donor; and, cycle control means for immediately switching from a withdraw cycle to a return cycle in response to said means for detecting and for immediately switching from a return cycle to a withdraw or stand-by cycle in response to said means for monitoring.
Claim 3
Dependent Claim
15 words
Plasmapheresis apparatus of claim 1 wherein said means for separating whole blood comprises a centrifuge.
Claim 4
Dependent Claim
44 words
Plasmapheresis apparatus of claim 2 wherein said means for monitoring comprises a monitor pouch formed from a flexible material capable of being distended under slight positive pressure and a weight sensor associated therewith for determining the weight of the contents of said monitor pouch.
Claim 5
Dependent Claim
17 words
Plasmapheresis apparatus of claim 3 wherein said means for withdrawing includes a phlebotomy needle and pressure cuff.
Claim 6
Dependent Claim
35 words
Plasmapheresis apparatus of claim 4 wherein said means for supplying anticoagulant comprises a supply of anticoagulant, an anticoagulant pump, and associated tubing connecting said supply to said pump and said pump to said phlebotomy needle.
Claim 7
Dependent Claim
54 words
Plasmapheresis apparatus of claim 5 wherein said means for transporting and said means for returning comprise a blood pump capable of operation in both forward and reverse modes, said blood pump having its inlet side connected by suitable tubing to the monitor pouch and its outlet side connected by suitable tubing to the centrifuge.
Claim 8
Dependent Claim
21 words
Plasmapheresis apparatus of claim 6 additionally including means to detect entrained gas bubbles within blood components being returned to a donor.
Claim 9
Dependent Claim
27 words
Plasmapheresis apparatus of claim 7 wherein said bubble means to detect includes a blood filter which is by-passable when the plasmapheresis apparatus is in a withdraw cycle.
Claim 10
Dependent Claim
112 words
A plasmapheresis centrifuge for separating whole blood into a plasma component and a non-plasma component, comprising, in combination: a rotatable centrifuge bowl formed from four integrally connected wall members consisting of an upper inclined wall member, a substantially vertical central wall member, a steeply pitched lower wall member, and a bottom wall member; a central core which defines a sedimentation area between said central core and the central wall member of said centrifuge bowl; inlet port means for admitting whole blood to said centrifuge bowl; outlet port means for removing separated plasma component from said centrifuge; and, rotary seal means for sealing the rotatable centrifuge bowl to stationary components of said centrifuge.
Claim 11
Dependent Claim
112 words
A plasmapheresis centrifuge for separating whole blood into a plasma component and a non-plasma component, comprising, in combination: a rotatable centrifuge bowl formed from four integrally connected wall members consisting of an upper inclined wall member, a substantially vertical central wall member, a steeply pitched lower wall member, and a bottom wall member; a central core which defines a sedimentation area between said central core and the central wall member of said centrifuge bowl; inlet port means for admitting whole blood to said centrifuge bowl; outlet port means for removing separated plasma component from said centrifuge; and, rotary seal means for sealing the rotatable centrifuge bowl to stationary components of said centrifuge.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-01 | 1981-10-31 | 1982-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-01 | 1985-10-31 | 1986-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-01 | 1989-10-31 | 1990-05-02 | $7700.00 | Window Closed / Lapsed |