Novel immunological adjuvant compounds and methods of preparation thereof

Claim 1

A compound selected from those of the formula: ##STR4## wherein each of R and R 1 are the same or different and are selected from the group consisting of hydrogen or an acyl radical containing from 1 to 22 carbon atoms; R 2 is selected from the group consisting of an unsubstituted or substituted alkyl radical containing from 1 to 22 carbon atoms, or an unsubstituted or substituted aryl radical containing from 6 to 10 carbon atoms; X is an aminoacyl moiety selected from the group consisting of L-alanyl, L-valyl, L-leucyl, L-isoleucyl, L-α-aminobutyryl, L-seryl, L-threonyl, L-methionyl, L-cysteinyl, L-phenylalanyl, L-tyrosyl, L-tryptophanyl, L-lysyl, L-ornithyl, L-arginyl, L-histidyl, L-glutamyl, L-glutaminyl, L-aspartyl, L-asparaginyl, L-prolyl, or L-hydroxyprolyl; Y is an amino acid moiety selected from the group consisting of D-isoasparagine and D-isoglutamine; and the wavy lines (ξ) represent the α- or β-configuration or mixtures thereof, with the proviso that when one wavy line is α, the other is β.