US4080455A
Expired / Lapsed
US
⏱️ 0.0 years remaining
5-Fluoropyrimidin-4-one compositions
Assignee: Taisho Pharmaceutical Co Ltd
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Filing: 1976-06-30
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Granted: 1978-03-21
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Expires: 1996-06-30
Abstract
Abstract A 5-fluoropyrimidin-4-one derivative represented by the formula <IMAGE> wherein R is straight-chain or branched-chain alkyl having 4 to 18 carbon atoms, straight-chain or branched-chain alkenyl having 2 to 18 carbon atoms, alkylene oxido having 3 to 10 carbon atoms, aryl or aralkyl; PROCESSES FOR PREPARING THE DERIVATIVE; AN ANTI-TUMOR COMPOSITION CONTAINING THE DERIVATIVE AS AN EFFECTIVE COMPONENT AND AN EXCIPIENT.
Inventors
- 👤 Mitugi Yasumoto
- 👤 Junichi Yamashita
- 👤 Ichiro Yamawaki
- 👤 Norio Unemi
- 👤 Kenji Kitazato
- 👤 Sadao Hashimoto
- 👤 Setsuro Fujii
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 17:41
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/52
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
36 words
An anti-tumor composition comprising a pharmacologically effective amount of the 5-fluoropyrimidin-4-one derivative represented by the formula ##STR7## wherein R is straight-chain or branched-chain alkyl having 4 to 6 carbon atoms, phenyl or benzyl, and an excipient.
Claim 2
Dependent Claim
36 words
An anti-tumor composition comprising a pharmacologically effective amount of the 5-fluoropyrimidin-4-one derivative represented by the formula ##STR7## wherein R is straight-chain or branched-chain alkyl having 4 to 6 carbon atoms, phenyl or benzyl, and an excipient.
Claim 3
Dependent Claim
26 words
The composition as defined in claim 1 for oral administration in the form of a tablet, capsule, soft capsule, granules, sustained release granules or fine particles.
Claim 4
Dependent Claim
22 words
The composition as defined in claim 2 for oral administration comprising 200 to 500 mg of the 5-fluoropyrimidin-4-one derivative per dosage unit.
Claim 5
Dependent Claim
13 words
The composition as defined in claim 1 in the form of a suppository.
Claim 6
Dependent Claim
19 words
The composition as defined in claim 4 comprising 500 to 1000 mg of the 5-fluoropyrimidin-4-one derivative per dosage unit.
Claim 7
Dependent Claim
13 words
The composition as defined in claim 1 in the form of an ointment.
Claim 8
Dependent Claim
17 words
The composition as defined in claim 6 comprising 5 to 10 wt. % of the 5-fluoropyrimidin-4-one derivative.
Claim 9
Dependent Claim
20 words
The composition of claim 1 wherein R is selected from the group consisting of n-butyl, s-butyl, n-hexyl, phenyl and benzyl.
Claim 10
Dependent Claim
17 words
The composition of claim 1 wherein R is selected from the group consisting of n-butyl and benzyl.
References Cited (Backward Citations)
US2802005A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-03-20 | 1981-09-19 | 1982-03-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-03-20 | 1985-09-19 | 1986-03-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-03-20 | 1989-09-19 | 1990-03-21 | $7700.00 | Window Closed / Lapsed |