US4080447A
Expired / Lapsed
US
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Therapeutic composition having an inhibiting activity on blood plate aggregation
Assignee: Sanofi SA
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Filing: 1976-03-29
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Granted: 1978-03-21
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Expires: 1996-03-29
Abstract
Abstract This invention relates to a therapeutic composition comprising, as active ingredient, a combination of 5-(2-chloro-benzyl)-4,5,6,7-tetrahydro-thieno[3,2-c]-pyridine and acetylsalicylic acid, the components of the combination being both present in the free state or as a pharmacologically acceptable salt. Said composition is useful both preventively and curatively for the treatment of thrombo-embolic diseases.
Inventors
- 👤 Armand Amselem
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 04:52
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/60
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
55 words
Therapeutic composition having an inhibiting activity on blood plate aggregation comprising, as active ingredient, a combination of 5-(2-chloro-benzyl)-4,5,6,7-tetrahydro-thieno-[3,2-c]-pyridine, hereinafter called ticlopidine, and acetylsalicylic acid, hereinafter called aspirin, formulated for the daily administration of 0.050-2 g ticlopidine and 0.100-4 g aspirin, the weight ratio of aspirin to ticlopidine being greater than one and up to four.
Claim 2
Dependent Claim
55 words
Therapeutic composition having an inhibiting activity on blood plate aggregation comprising, as active ingredient, a combination of 5-(2-chloro-benzyl)-4,5,6,7-tetrahydro-thieno-[3,2-c]-pyridine, hereinafter called ticlopidine, and acetylsalicylic acid, hereinafter called aspirin, formulated for the daily administration of 0.050-2 g ticlopidine and 0.100-4 g aspirin, the weight ratio of aspirin to ticlopidine being greater than one and up to four.
Claim 3
Dependent Claim
18 words
Therapeutic composition as claimed in claim l, wherein the active ingredient is combined with a pharmacologically acceptable carrier.
Claim 4
Dependent Claim
30 words
Therapeutic composition as claimed in claim 1, wherein each component of the conbination is present in a chemical form selected from the free compound and a pharmacologically acceptable salt thereof.
Claim 5
Dependent Claim
57 words
Therapeutic composition having an inhibiting activity on blood plate aggregation comprising, an active ingredient, a combination of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydro-thieno-[3,2-c]-pyridine, hereinafter called ticlopidine, and acetylsalicylic acid, hereinafter called aspirin, in unit dosage form, each unit does containing 0.050-0.7 g ticlopidine and 0.100-0.9 g aspirin, the weight ratio of aspirin to ticlopidine being greater than one and up to four.
Claim 6
Dependent Claim
57 words
Therapeutic composition having an inhibiting activity on blood plate aggregation comprising, an active ingredient, a combination of 5-(2-chlorobenzyl)-4,5,6,7-tetrahydro-thieno-[3,2-c]-pyridine, hereinafter called ticlopidine, and acetylsalicylic acid, hereinafter called aspirin, in unit dosage form, each unit does containing 0.050-0.7 g ticlopidine and 0.100-0.9 g aspirin, the weight ratio of aspirin to ticlopidine being greater than one and up to four.
Claim 7
Dependent Claim
18 words
Therapeutic composition as claimed in claim 4, wherein the active ingredient is combined with a pharmacologically acceptable carrier.
Claim 8
Dependent Claim
30 words
Therapeutic composition as claimed in claim 4, wherein each component of the combination is present in a chemical form selected from the free compound and a pharmacologically acceptable salt thereof.
Claim 9
Dependent Claim
14 words
Therapeutic composition as claimed in claim 1, wherein said weight ratio is about 1:1.
Claim 10
Dependent Claim
14 words
Therapeutic composition as claimed in claim 1, wherein said weight ratio is about 1:2.5.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-03-20 | 1981-09-19 | 1982-03-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-03-20 | 1985-09-19 | 1986-03-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-03-20 | 1989-09-19 | 1990-03-21 | $7700.00 | Window Closed / Lapsed |