US4080328A
Expired / Lapsed
US
⏱️ 0.0 years remaining
N-substituted heterocyclic derivatives and preparation thereof
Assignee: Sumitomo Chemical Co Ltd
•
Filing: 1974-06-28
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Granted: 1978-03-21
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Expires: 1994-06-28
Abstract
Abstract Novel N-substituted heterocyclic derivatives represented by the formula, ##STR1## wherein R is hydrogen or lower alkanoyl; R 1 is hydrogen, lower alkyl, lower alkoxy, halogen, nitro, trifluoromethyl, amino or N-lower alkanoylamino; R 2 is hydrogen, halogen, amino or N-lower alkanoylamino; W is oxygen, sulfur, sulfinyl or sulfonyl; and Y is ##STR2## (wherein R 3 is hydrogen, lower alkyl or lower alkanoyl; and R 4 is hydrogen, halogen or lower alkyl), and pharmaceutically acceptable salts thereof, which have excellent anti-inflammatory, analgesic, sedative, anti-convulsive or anti-hypertensive activities.
Inventors
- 👤 Isamu Maruyama
- 👤 Masaru Nakao
- 👤 Kikuo Sasajima
- 👤 Shigeho Inaba
- 👤 Izumi Yanagihara
- 👤 Hisao Yamamoto
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 16:25
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/06; C07D401/04; C07D401/12; C07D401/14; C07D405/00; C07D405/14
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
55 words
A chemical compound selected from the group consisting of a benzimidazoline derivative having the formula: ##STR11## and the therapeutically active acid addition salts thereof, wherein R 1 is a member selected from the group consisting of hydrogen, halo, and loweralkoxy; and R 2 is a member selected from the group consisting of hydrogen and halo.
Claim 2
Dependent Claim
55 words
A chemical compound selected from the group consisting of a benzimidazoline derivative having the formula: ##STR11## and the therapeutically active acid addition salts thereof, wherein R 1 is a member selected from the group consisting of hydrogen, halo, and loweralkoxy; and R 2 is a member selected from the group consisting of hydrogen and halo.
Claim 3
Dependent Claim
1 words
1-{1-[3-p-Fluorophenoxy-2-hydroxypropyl]-4-piperidyl}-2-oxobenzimidazoline.
Claim 4
Dependent Claim
1 words
1-{1-[3-p-Fluorophenoxy-2-hydroxypropyl]-4-piperidyl}-2-oxobenzimidazoline.
References Cited (Backward Citations)
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US3196157A
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US3238216A
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Cited
NL7211619A
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US3818017A
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US3894030A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-03-20 | 1981-09-19 | 1982-03-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-03-20 | 1985-09-19 | 1986-03-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-03-20 | 1989-09-19 | 1990-03-21 | $7700.00 | Window Closed / Lapsed |