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US4076711A Expired / Lapsed US ⏱️ 0.0 years remaining

Triazolo [4,5-d]-pyrimidines

Assignee: Merck Sharp & Dohme LLC
•
Filing: 1976-12-22
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Granted: 1978-02-28
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Expires: 1996-12-22
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Abstract

Abstract This disclosure relates to the method for the treatment of psoriasis which comprises the topical administration to a mammal suffering from psoriasis of an effective dose for treating psoriasis of a 7X-5Q-3Y-3H- gamma -triazolo[4,5-d]-pyrimidine wherein X is halogeno, alkoxy, or -NRR1, R and R1 being lower alkyl, Y is cycloalkyl, hydroxycycloalkyl, phenyl, bicycloalkyl, or A-R2 with A being methylene or ethylene and R2 being phenyl or bicycloalkyl, and Q is hydrogen or Y.

Inventors

  • 👤 Ashit K. Ganguly
  • 👤 Edwin A. Peets
  • 👤 Anil K. Saksena

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 22:57
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/48; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61P; A61P17/00; C07D487/00; C07D487/02; C07D487/04

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 9 words
A compound selected from the group consisting of 7-chloro-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 2
Dependent Claim 9 words
A compound selected from the group consisting of 7-chloro-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 3
Dependent Claim 1 words
7-chloro-3-cycloheptyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 4
Dependent Claim 1 words
7-chloro-3-cycloheptyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 5
Dependent Claim 1 words
7-chloro-3-cyclobutyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 6
Dependent Claim 1 words
7-chloro-3-cyclobutyl-3H-γ-triazolo[4,5-d]-pyrimidine,
Claim 7
Dependent Claim 2 words
7-iodo-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine, and
Claim 8
Dependent Claim 2 words
7-iodo-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine, and
Claim 9
Dependent Claim 1 words
7-methoxy-3-cyclopentyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 10
Dependent Claim 1 words
7-methoxy-3-cyclopentyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 11
Dependent Claim 9 words
A compound of claim 1, said compound being 7-chloro-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 12
Dependent Claim 9 words
A compound of claim 1, said compound being 7-chloro-3-cycloheptyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 13
Dependent Claim 9 words
A compound of claim 1, said compound being 7-chloro-3-cyclobutyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 14
Dependent Claim 9 words
A compound of claim 1, said compound being 7-iodo-3-cyclohexyl-3H-γ-triazolo[4,5-d]-pyrimidine.
Claim 15
Dependent Claim 9 words
A compound of claim 1, said compound being 7-methoxy-3-cyclopentyl-3H-γ-triazolo[4,5-d]-pyrimidine.

References Cited (Backward Citations)

US2407204A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-02-27 1981-08-29 1982-02-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-02-27 1985-08-29 1986-02-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-02-27 1989-08-29 1990-02-28 $7700.00 Window Closed / Lapsed

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