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US4075405A Expired / Lapsed US ⏱️ 0.0 years remaining

β-1,3-Glucan derivatives

Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1975-11-26
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Granted: 1978-02-21
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Expires: 1995-11-26
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Abstract

Abstract β-1,3-Glucan derivatives, which are produced by reacting a water-insoluble β-1,3-glucan with a cyanogen halide, are a useful water-insoluble carrier of high reactivity for the production of water-insoluble enzymes and of carrier-ligand products suitable for affinity chromatography.

Inventors

  • 👤 Takeshi Takahashi
  • 👤 Yoshio Yamazaki
  • 👤 Koichi Kato

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 06:58
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0024; B; B01; B01J; B01J20/00; B01J20/281; B01J20/286; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/823; Y10S435/829; Y10S435/91

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 73 words
A beta-1,3-glucan derivative, which is produced by reacting water-insoluble beta-1,3-glucan produced by microorganisms belonging to the genus Alcaligenes, the genus Agrobacterium or Poria cocos, with cyanogen halide in the presence of water and with the addition of an alkali in an amount such that the pH of the reaction system is sufficiently increased to prevent dissolution of said water-insoluble beta-1,3-glucan, said increase being in the range of about 0.2 to 0.5 pH unit/minute.
Claim 2
Dependent Claim 73 words
A beta-1,3-glucan derivative, which is produced by reacting water-insoluble beta-1,3-glucan produced by microorganisms belonging to the genus Alcaligenes, the genus Agrobacterium or Poria cocos, with cyanogen halide in the presence of water and with the addition of an alkali in an amount such that the pH of the reaction system is sufficiently increased to prevent dissolution of said water-insoluble beta-1,3-glucan, said increase being in the range of about 0.2 to 0.5 pH unit/minute.
Claim 3
Dependent Claim 17 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is in the form of powder.
Claim 4
Dependent Claim 17 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is in the form of fiber.
Claim 5
Dependent Claim 17 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is in the form of film.
Claim 6
Dependent Claim 17 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is in the form of bead.
Claim 7
Dependent Claim 21 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is produced by a microorganism belonging to the genus Alcaligenes.
Claim 8
Dependent Claim 21 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is produced by a microorganism belonging to the genus Agrobacterium.
Claim 9
Dependent Claim 20 words
A beta-1,3-glucan derivative according to claim 1, wherein the water-insoluble beta-1,3-glucan is produced by a microorganism belonging to Poria cocos.

References Cited (Backward Citations)

US3423288A Cited
US3396082A Cited
US3645852A Cited
US3759896A Cited
US3822250A Cited
US3899480A Cited
US3900462A Cited
US3870537A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-02-20 1981-08-22 1982-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-02-20 1985-08-22 1986-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-02-20 1989-08-22 1990-02-21 $7700.00 Window Closed / Lapsed

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